Results 61 to 70 of about 12,375,897 (253)
Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah +5 more
wiley +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Polyamines in human health [PDF]
Summary Overall, polyamine depletion by a variety of strategies can be successful in preventing or inhibiting the growth of tumours in animal models and to some extent in man. The development of new drugs, such as the MGBG analogues synthesized by Ciba Geigy (Basel, Switzerland) which are competitive inhibitors of AdoMetDC (Regenass et al.
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Humanities, Science, and Technology
Application instructions and forms for humanities, science, and technology ...
National Endowment for the Humanities, Division of Research Programs
core
An examination of the physical and the digital qualities of humanities research [PDF]
Traditionally humanities scholars have worked in physical environments and with physical artefacts. Libraries are familiar places, built on cultural traditions over thousands of years, and books are comfortable research companions.
Rimmer, J +9 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Humanities, Science, and Technology
Application instructions and forms for humanities, science, and technology ...
National Endowment for the Humanities, Division of Research Programs
core
A Typology of the Publicly Engaged Humanities [PDF]
This essay outlines five types of publicly engaged humanities work. It was originally published in 2018 on the Humanities for All website, an initiative of the National Humanities Alliance Foundation. With the support of the Andrew W.
Daniel Fisher
core +1 more source

