Results 201 to 210 of about 2,251,189 (267)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Evaluation of spondyloarthritis-specific health utility based on ASAS health index (U-ASAS-HI) among the disease subtypes: an ancillary analysis from the ASAS-PerSpA study. [PDF]

open access: yesRMD Open
Calixto OJ   +8 more
europepmc   +1 more source

Commentary: The ME-BYO index: A development and validation project of a novel comprehensive health index. [PDF]

open access: yesFront Public Health
Ikewaki N   +4 more
europepmc   +1 more source

Mental health index of the elderly population in Medellín (Colombia)-2021: a factorial analysis. [PDF]

open access: yesFront Psychol
Ochoa-Nieto SP   +5 more
europepmc   +1 more source

Comparison of Single Polygenic, Multiple Polygenic Risk, and Lifestyle for Brain Health Index in Explaining Cognitive Function Among Middle-aged and Older Adults in The Maastricht Study

open access: yes
Zhang Y   +11 more
europepmc   +1 more source

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