Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Oral Health Index for Children: A Novel System Introduction Assessing the Oral Hygiene Status of Primary and Mixed Dentition. [PDF]
Takate V +4 more
europepmc +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Evaluation of spondyloarthritis-specific health utility based on ASAS health index (U-ASAS-HI) among the disease subtypes: an ancillary analysis from the ASAS-PerSpA study. [PDF]
Calixto OJ +8 more
europepmc +1 more source
Commentary: The ME-BYO index: A development and validation project of a novel comprehensive health index. [PDF]
Ikewaki N +4 more
europepmc +1 more source
The combination of prostate health index and multiparametric magnetic resonance imaging in prostate cancer diagnosis: efficacy analysis in different PSA ranges and its clinical decision-guiding value. [PDF]
Pan JF +8 more
europepmc +1 more source
Mental health index of the elderly population in Medellín (Colombia)-2021: a factorial analysis. [PDF]
Ochoa-Nieto SP +5 more
europepmc +1 more source
Diagnostic value of prostate health index in patients with no index lesion on mpMRI or negative previous combined biopsy. [PDF]
Jeon SS +7 more
europepmc +1 more source
Weighted predictive modelling estimation of patient acceptable symptom state for forgotten joint score, Oxford hip score, and EuroQol health index 3 and 12 months after total hip arthroplasty in a United Kingdom cohort. [PDF]
Abugu GU +5 more
europepmc +1 more source

