Results 171 to 180 of about 7,648,901 (345)

An Introduction to Clinical Informatics for Early Medical Learners Using Colorectal Cancer Screening

MedEdPORTAL
Introduction Clinical informatics is an important component of the AMA-endorsed third pillar of undergraduate medical education, health systems science.
Alan Williams, Kasi Chu, Colby Uptegraft, Joshua Duncan   +3 more
doaj   +1 more source

Evidence based healthcare planning in developing countries: An Informatics perspective [PDF]

, 2009
Most of the national Health Information Systems (HIS) in resource limited developing countries do not serve the purpose of management support and thus the service is adversely affected.
Ranasinghe, Kaduruwane, Sahama, Tony, Yarlagadda, Prasad   +2 more
core   +1 more source

Rethinking the AI Paradigm for Solubility Prediction of Drug‑Like Compounds with Dual‐Perspective Modeling and Experimental Validation

Advanced Science, EarlyView.
Aqueous solubility governs drug delivery and bioavailability, yet its prediction remains challenging. Utilizing the largest curated dataset of drug‐like molecules, prediction models are constructed through dual‐perspective benchmarking. Stacking methods outperform advanced deep learning due to data constraints. These validated models enabled systematic
Qilin Zhu, Yuxin Qiu, Guzhong Chen, Wenyao Chen, Xiang Zhang, Zhiwen Qi, Xuezhi Duan, De Chen, Zhen Song   +8 more
wiley   +1 more source

Detecting and Filtering Immune-Related Adverse Events Signal Based on Text Mining and Observational Health Data Sciences and Informatics Common Data Model: Framework Development Study [PDF]

, 2020
Yue Yu, Kathryn J. Ruddy, Aaron S. Mansfield, Nansu Zong, Andrew Wen, Shintaro Tsuji, Ming Huang, Hongfang Liu, Nilay D. Shah, Guoqian Jiang   +9 more
openalex   +1 more source

A Proposed Approach to Investigate Whether Postgraduate Health Care Management Education in Australian Universities Facilitates the Development of Informatics Competencies [PDF]

, 2021
Mark Brommeyer, Mark MacKay, Zhanming Liang, Louise Schaper, Peter Balan   +4 more
openalex   +1 more source

Immunoregulatory Roles of Tumor‐Originated Pericytes Identified by Single‐Cell Analysis in Glioblastoma

Advanced Science, EarlyView.
The origin and functional heterogeneity of pericytes in glioblastoma (GBM) remain unclear. This study identifies tumor‐originated pericytes (T‐PCs) and normal‐originated pericytes as two distinctive populations in human GBM using single‐cell RNA‐sequencing.
Cuiying Chu, Fangzhen Li, Zhiwen Zhang, Qiuhong Zhu, Hong Yan, Mengdan Cheng, Huipeng Wang, Lei Cheng, Zhe Zhang, Xingjiang Yu, Jianghong Man, Wei Wang, Dongxue Li, Xiu‐wu Bian, Hai‐bo Wu, Aili Zhang, Wenchao Zhou   +16 more
wiley   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

Advanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna, Jinshan He, Jiaxing Miao, Nargis Shaheen, Boyu Xia, Cankun Wang, Qin Ma, Matthew C Bernier, Bryan A Whitson, Nuo Sun, Jing Zhao, Yutong Zhao   +11 more
wiley   +1 more source

Biomedical and health informatics teaching in Portugal: Current status

, 2023
Paulo Dias Costa, João Coutinho‐Almeida, Sabrina Magalhães Araujo, Patrícia Alves, Ricardo Cruz‐Correia, Kaija Saranto, John Mantas   +6 more
openalex   +1 more source

Cerebral palsy and epilepsy: a health informatics approach [PDF]

, 2021
Richard Chin
openalex   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source