Results 71 to 80 of about 7,306,095 (347)

Transparency of Health Informatics Processes as the Condition of Healthcare Professionals’ and Patients’ Trust and Adoption: the Rise of Ethical Requirements

Yearbook of Medical Informatics, 2020
Summary Objectives: To provide an introduction to the 2020 International Medical Informatics Association (IMIA) Yearbook by the editors. Methods: This editorial provides an introduction and overview to the 2020 IMIA Yearbook which special topic is ...
B. Séroussi, K. Hollis, L. Soualmia
semanticscholar   +1 more source

Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis

FEBS Letters, EarlyView.
Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner, Juthamas Khamseekaew, M. Gregor Madej, Linda Geiges, Bardha Azemi, Christine Ziegler, Christoph Korbmacher, Alexandr V. Ilyaskin   +7 more
wiley   +1 more source

Health information systems in Jordan and Palestine: the need for health informatics training.

Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 2020
Background Some Arab countries have health information systems (HIS) in place but they lack well trained IT staff. Poor management and lack of appreciation of the importance of HIS are major barriers to development and adoption of HIS in Arab hospitals.
Hussein M. Jabareen, Y. Khader, A. Taweel   +2 more
semanticscholar   +1 more source

Gut microbiota diversity is prognostic and associated with benefit from chemo‐immunotherapy in metastatic triple‐negative breast cancer

Molecular Oncology, Volume 19, Issue 4, Page 1229-1243, April 2025.
We assessed the associations between the gut microbiota and outcome in metastatic triple‐negative breast cancer patients treated with chemotherapy alone or chemotherapy in combination with immunotherapy. Our data indicate that high gut microbiota alpha diversity was associated with improved clinical outcome and with benefit from immunotherapy.
Andreas Ullern, Kristian Holm, Andreas Hagen Røssevold, Nikolai Kragøe Andresen, Corinna Bang, Ole Christian Lingjærde, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +8 more
wiley   +1 more source

Automatic skin lesion segmentation with fully convolutional-deconvolutional networks [PDF]

IEEE Journal of Biomedical and Health Informatics, 2018, 2017
This paper summarizes our method and validation results for the ISBI Challenge 2017 - Skin Lesion Analysis Towards Melanoma Detection - Part I: Lesion ...
arxiv   +1 more source

Nursing informatics: a personal review of the past, the present and the future [PDF]

, 2005
There is evidence that nurses have been involved in, or have been affected by health- related computer projects since the mid-1960's. Since those early years nurses have made many significant contributions to the wider bio-health informatics agenda ...
Hardiker, NR, Hyeoun-Ae, P
core   +1 more source

NanoCMSer: a consensus molecular subtype stratification tool for fresh‐frozen and paraffin‐embedded colorectal cancer samples

Molecular Oncology, Volume 19, Issue 5, Page 1332-1346, May 2025.
Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang, Simone van de Weerd, Veerle Lammers, Sander van Hooff, Inge van den Berg, Saskia van den Bergh, Miriam Koopman, Jan N. IJzermans, Jeanine M. L. Roodhart, Jan Koster, Jan Paul Medema   +10 more
wiley   +1 more source

Online digital health and informatics education for undergraduate nursing students in China: impacts and recommendations

BMC Medical Education
Background Digital health plays a vital role in healthcare services. Governments in many countries, including China, are increasingly advocating for the appropriate use of digital technologies to address significant health system challenges.
Hongxia Shen, Chong Chen, Sijing Yan, Cynthia Hallensleben, Rianne van der Kleij, Minyi Li, Huohuo Dai, Niels Chavannes, Ying Zhou   +8 more
doaj   +1 more source

Informatics Competencies of Students in a Doctor of Nursing Practice Program: A Descriptive Study [PDF]

Healthcare Informatics Research
Objectives Health systems that apply artificial intelligence (AI) are transforming the roles of healthcare providers, including those of Doctor of Nursing Practice (DNP) providers.
Jeeyae Choi, Seoyoon Woo, Valerie Tarte
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source