Results 81 to 90 of about 5,456,254 (267)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Current status of short video as a source of information on lung cancer: a cross-sectional content analysis study

open access: yesFrontiers in Oncology
BackgroundThe morbidity and mortality rates of lung cancer continue to rise, leading to a significant disease burden. Health education on lung cancer serves as an effective approach for prevention and treatment.
Xinyu Zhao   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Health information post-encountering behaviours on social media platforms

open access: yesInformation Research: An International Electronic Journal
Introduction. While much research has been done into how people encounter information, little has investigated post-encountering behaviours and their motivating factors.
Khalid U Fallatah   +2 more
doaj  

Changing roles of health information managers: An education perspective

open access: yes, 2009
Health information management graduates are employed across health, education, corporate and other sectors. Common to all health information management professionals are foundational skills and knowledge in health sciences, information and management ...
Cooper, Helen
core  

Aurora Libraries Health Information Service Brochure, 1996

open access: yes, 2020
Aurora Health Care Libraries, Wisconsin: This 1996 brochure contains information for patients about services available from Aurora Libraries, part of Aurora Health Care.https://institutionalrepository.aah.org/ahc_books/1144/thumbnail ...
Advocate Aurora Health
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Evaluation of Self-Ratings for Health Information Behaviour Skills Requires More Heterogeneous Sample, but Finds that Public Library Print Collections and Health Information Literacy of Librarians Needs Improvement

open access: yesEvidence Based Library and Information Practice, 2016
Objective – To understand public library users’ perceptions of ability to locate, evaluate, and use health information; to identify barriers experienced in finding and using health information; and to compare self-ratings of skills to an administered ...
Carol Perryman
doaj  

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