Results 201 to 210 of about 9,121,442 (394)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

A Data-Driven Paradigm for a Resilient and Sustainable Integrated Health Information Systems for Health Care Applications. [PDF]

J Multidiscip Healthc, 2023
Epizitone A, Moyane SP, Agbehadji IE.
europepmc   +1 more source

Information Systems to facilitate Health and Clinical Management [PDF]

, 2001
Lyn A Hanmer
openalex   +1 more source

Health Information Systems [PDF]

Yearbook of Medical Informatics, 2004
openaire   +1 more source

Using routine health information systems for well-designed health evaluations in low- and middle-income countries.

Health Policy and Planning, 2016
B. Wagenaar, K. Sherr, Quinhas Fernandes, A. Wagenaar   +3 more
semanticscholar   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

Validation of pharmaceutical information systems: general provisions

Регуляторные исследования и экспертиза лекарственных средств, 2018
Nternational practices comprise integrated common approaches to validation of information systems, used in pharmaceutical industry by various organizations and that affect the results of their work. The purpose ofvalidation is to assure that the results,
K. A. Koshechkin, E. V. Gladkaya, Ya. Yu. Kondratieva   +2 more
doaj  

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Health information systems for leprosy control programmes: a case for quality assessment

, 1996
Daniel Grodos, Isabelle François, René Tonglet   +2 more
openalex   +1 more source

Inter-organizational collaboration among health and social care: TRT©, a transactional approach [PDF]

Inter-organizational collaboration (IOC) supported by information and communication technologies (ICTs) faces challenges on many fronts in 21st century England as well as globally.
Louws, Margie
core