Results 241 to 250 of about 1,959,318 (304)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Intrafacility Neonatal Intensive Care Unit to Pediatric Intensive Care Unit Transfer in the United States: A Pediatric Health Information Systems Registry Study. [PDF]

J Pediatr Clin Pract
Cohen PD, Gontasz MM, Bernier M, Zaniletti I, Kudchadkar SR, Sochet AA, Stockwell DC.   +6 more
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Assessing the integration of refugee health data into national health information systems in Jordan, Lebanon, and Uganda. [PDF]

Confl Health
Bou-Karroum L, Daher N, Jabbour M, Akhu-Zaheya L, Khater W, Alloubani A, Orach CG, Komakech H, Bennett S, El-Jardali F.   +9 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Community-Based Health Information Systems in Africa: A Scoping Review of Data Generation, Utilization, and Community Empowerment. [PDF]

Wellcome Open Res
Kuvuna B, Nyanchoka M, Guleid F, Ogutu M, Tsofa B, Nzinga J.   +5 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Investigating the role of Cybersecurity's perceived threats in the adoption of health information systems. [PDF]

Heliyon
Zhan Y, Ahmad SF, Irshad M, Al-Razgan M, Awwad EM, Ali YA, Ahmad Ayassrah AYAB.   +6 more
europepmc   +1 more source

Health Information Systems

Yearbook of Medical Informatics, 2008
openaire   +1 more source