Results 141 to 150 of about 1,607,450 (303)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
La salud móvil y los sistemas de salud: Determinantes del progreso en la salud global
Revista Peruana de Medicina Experimental y Salud PúblicaPor lo general, cuando se habla sobre tecnologías de la información suele hablarse sobre la tecnología en sí y su contenido. En este artículo quisiera enfocarme en las tecnologías móviles para la salud (salud móvil), pero no tanto en su contenido de la ...
Julio Frenk
doaj +2 more sources
FEBS Open Bio, EarlyView.We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa +2 more
wiley +1 more source
Integrating health care with information and communication technology
International Journal of Integrated Care, 2010 Anne Moen
doaj +3 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Identifying benefits and barriers for IS adoption: A sociotechnical framework applied to health care
, 2007 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 13/11/2007.The aim of this research is to propose a sociotechnical framework to identify stakeholders involved in information systems and the benefit and ...
Piris Pinilla, Maria Luisa
core
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
, 2010 New information technologies (IT) in healthcare systems promise a variety of benefits, such as reduced healthcare costs, yet enjoy comparatively little adoption and often fall short of their potential.
PCAST Health Information Technology Working Group +2 more
core