Results 111 to 120 of about 14,289,273 (258)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Innovative tracks at established institutions for the education of health personnel : an experimental approach to change relevant to health needs / Martin Kantrowitz ... [et al.]

open access: yes, 1987
232 p.Provides a highly practical and instructive guide for educators seeking to reform programmes and methods of teaching at established medical schools. Focused on practical problems, the book describes an approach to change involving the establishment
Kaufman, Arthur   +6 more
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Standards for public institutions

open access: yes, 1973
Developed under authority of the State Board of Institutional Trustees by the operating divisions of the Dept.
New Jersey. Department of Institutions and Agencies
core  

A compendium of selected databases maintained by the State of Connecticut, Department of Public Health. December 2003.

open access: yes, 2003
Electronic data; Title from PDF cover (viewed Dec. 21, 2005).; Prepared by the Bureaus of Community Health (BCH), Public Health Science (BPHS), and Regulatory Services (BRS).; "December 2003."; Harvested from the web on 12/22 ...
Connecticut. Dept. of Public Health.
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Factores que intervienen en la utilización de los servicios de salud por el adulto mayor ª Tampico - Tamaulipas - México 2003-2004 Factors that take part in the usage of the health services from senior adults

open access: yesInvestigación y Educación en Enfermería, 2006
Objetivo: Evaluar factores que podrían restringir o favorecer el uso de los centros comunitarios y de otras instituciones de salud (seguridad social, consulta privada y otros) en adultos mayores de 60 años o más en Tampico, Tamaulipas, México. Material y
Maria Isabel Peñarrieta de Córdova   +4 more
doaj  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

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