Results 111 to 120 of about 1,781,732 (310)

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Segregated prisoners: nature imagery project in prisons as a program option [PDF]

, 2018
Master's Project (M.A.) University of Alaska Fairbanks, 2018Solitary confinement can be summarized as the state of being alone in a prison cell for 22 to 24 hours a day with minimal human interaction, little to no natural light, property restrictions ...
Schwankl, Kristine
core  

Liquid Hydroxyurea (Xromi) for Children With Sickle Cell Anemia: A New Solution Compounding Existing Problems

Pediatric Blood &Cancer, EarlyView.
Alexandra Power‐Hays, Charles T. Quinn
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Global, regional, and national burden of varicella-zoster infections in adults aged 70 years and older from 1997 to 2021: Findings from the Global Burden of Disease Study

Journal of Infection and Public Health
Background: Varicella-zoster virus (VZV) infection gives rise to varicella (chickenpox) and herpes zoster (HZ, shingles). Primary VZV infection results in varicella, while HZ occurs as a consequence of latent VZV reactivation.
Chenchen Yang, Zhenpeng Guo, Xiaowei Deng, Yanling Wei, Qun Zhang, Jianming Wang   +5 more
doaj   +1 more source

Anti-corruption management in the health care system: the legal aspect

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
The purpose of the research. To analyze the concept of anti-corruption management and organizational and legal aspects of the implementation of anti-corruption activities in health care institutions, on the basis of the analyzed material, to define the ...
М. А. Anishchenko
doaj   +1 more source

Can local institutions reduce poverty? Rural decentralization in Burkina Faso [PDF]

The authors present evidence that in Burkina Faso, certain high-performing local institutions contribute to equitable economic development. They link reduced levels of poverty, and inequality to a high degree of internal village organization.
Donnelly-Roark, Paula, Ouedraogo, Karim, Xiao Ye   +2 more
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Los valores como núcleo de la gestión de las instituciones de salud en Cuba

Revista Médica Electrónica
RESUMEN Se realizó una revisión de los conceptos más conocidos dentro del ámbito organizacional que abordan al valor como categoría científica. Se analizan y se destacan sus principales aportes al mundo laboral.
Armenio Pérez Martínez, Aimara Rodríguez Fernández   +1 more
doaj