Results 141 to 150 of about 7,069,482 (314)

Knowledge management: Using a knowledge requirements framework to enhance UK health sector supply chains [PDF]

, 2008
The gaps of mismatch both knowledge and understanding of beneficiaries and solution providers at the initial stage of developing projects have led to the failures of many projects including supply chains (SC) and related information technology systems (
Al-Karaghouli, W, Alshawi, S, Taylor, P
core  

Personalized Health Knowledge Graph.

CEUR workshop proceedings, 2020
Our current health applications do not adequately take into account contextual and personalized knowledge about patients. In order to design "Personalized Coach for Healthcare" applications to manage chronic diseases, there is a need to create a Personalized Healthcare Knowledge Graph (PHKG) that takes into consideration a patient's health condition ...
Gyrard, Amelie, Gaur, Manas, Shekarpour, Saeedeh, Thirunarayan, Krishnaprasad, Sheth, Amit   +4 more
openaire   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Knowledge Translation in Health Research [PDF]

, 2020
Leggett, Carly
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Lost in Knowledge Translation: Moving Towards a Clearer Picture? Mapping the conceptualisation of knowledge translation, transfer and exchange across public health in the North East [PDF]

, 2012
Over recent decades the concept of evidence-based practice in health care has become part of the language of practitioners, policymakers and researchers.
Goodall, Deborah, Steven, Alison, Visram, Shelina   +2 more
core  

"Knowledge for Health": Integrated health care

Annales Kinesiologiae, 2023
Boštjan Šimunić, Nika Štravs, Matej Kleva, Peter Čerče   +3 more
openaire   +3 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Collecting and using social needs data in health settings: a systematic review of the literature on health service utilization and costs

BMC Health Services Research
Background Social determinants of health significantly influence health outcomes and contribute to health inequities across populations. Systematic and routine collection of social needs data and its use to inform interventions within healthcare settings
Mélanie Ann Smithman, Oluwasegun J. Ogundele, Laure Perrier, Menna Komeiha, Iryna Artyukh, Paras Kapoor, Andrew D. Pinto   +6 more
doaj   +1 more source