The effect of smartphones on the self-rated health levels of the elderly. [PDF]
BMC Public Health, 2022 Liang X, Xiong F, Xie F.
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Changes in mental health levels among Chinese physical education college students from 1995 to 2019. [PDF]
Front Psychol, 2022 Li F +5 more
europepmc +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Modern GeográfiaThe study examines the spatial characteristics of ambulance stations in Hungary. After 1948, the location of these stations changed mainly during the 1950s and 1960s, particularly in settlements with a population of over 10,000.
Ecsegi, Dániel, Kozma, Gábor
doaj +1 more source
The Impact of Multidimensional Health Levels on Rural Poverty: Evidence from Rural China. [PDF]
Int J Environ Res Public Health, 2022 Chen X, Zhou T, Wang D.
europepmc +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
The moderating role of sociodemographic and work-related variables in burnout and mental health levels of Mexican medical residents. [PDF]
PLoS One, 2022 Dominguez-Espinosa ADC +4 more
europepmc +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source
Opioid prescribing for acute postoperative pain: an overview of systematic reviews related to two consensus statements relevant at patient, prescriber, system and public health levels. [PDF]
BMC Anesthesiol, 2023 McCorquodale CL +3 more
europepmc +1 more source