Results 121 to 130 of about 3,591,872 (263)

Technology-based physical activities and adults' physical activity levels, mental health, life satisfaction, and happiness: a mixed methods study. [PDF]

BMC Psychol
Lu Z, Xiang J, Li S, Zhang C, Wu C.
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Effectiveness of cognitive-behavioral therapy on mental health, life expectancy, and happiness in patients receiving methadone maintenance treatment. [PDF]

J Educ Health Promot
Amiri P, Rasouli-Azad M, Afshari B, Chehri A, Amiri M, Rezaie Z.   +5 more
europepmc   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Examining the associations between mental health, life balance, work-method autonomy, and perceived boundary control among postdoctoral fellows. [PDF]

Front Psychol
Lo BK, Park IY, Choung D, McTernan M, Sibley E, Davison KK.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Echoes of conflict and displacement in maternal health: Life-course violence, timing, and maternal stress after childbirth at the northern Thailand-Myanmar border. [PDF]

Psychoneuroendocrinology
Koning SM, Adam EK, Kapoor A, McDade TW.
europepmc   +1 more source

Health, life and rights: a discourse analysis of a hybrid abortion regime in Tanzania. [PDF]

Int J Equity Health, 2019
Sambaiga R, Haukanes H, Moland KM, Blystad A.   +3 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

[Impact of Community Leader-driven Neighborhood Care Programs on Older Adults' Self-rated Health, Life Satisfaction, and Quality of Life]. [PDF]

Jugan Geongang Gwa Jilbyeong
Yim E, Kim J, Lee I, Hong H, Lee D, Nam M, Yang M, Lee K.   +7 more
europepmc   +1 more source