Results 101 to 110 of about 1,861,055 (314)

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

The Critical Role and Effects of Patient-Centered Communication in Psychotherapy: A Narrative Review

open access: yesPsychology Research and Behavior Management
Yaohong Niu,1,* Jingbo Sun,2,* Kerun Zhu,1 Bojun Xu,1 Yin-Ping Zhang,3 Min Peng3 1School of Journalism and New Media, Xi’an Jiaotong University, Xi’an, 710049, People’s Republic of China; 2School of Sport Management and Communication ...
Niu Y   +5 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Potential of social media in promoting mental health in adolescents

open access: yes, 2018
The growing prevalence of adolescent mental disorders poses significant challenges for education and healthcare systems globally. Providers are therefore keen to identify effective ways of promoting positive mental health.
Reilly, Paul   +5 more
core   +1 more source

RELATIONSHIP BETWEEN THE HEALTH AND MEDIA LITERACY - SAĞLIK VE MEDYA OKURYAZARLIK ARASINDAKİ İLİŞKİ

open access: yesMehmet Akif Ersoy Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2017
Health literacyand media literacy are important indicators for development a region. Aim ofthe study was to determine the health and media literacy levels of people andthe relationship between two types of literacy in Mut County, Mersin/Turkey.
Şerife Didem Kaya, Ayhan Uludağ
doaj   +1 more source

MEDIA AND WOMEN HEALTH IN INDIA

open access: yesInternational Journal of Research -GRANTHAALAYAH, 2016
Health Communication is an important domain in communication arena aims at disseminating health messages to the public. In this study the role of media in giving health information to women is analysed. The portrayal of women in media, the impact it creates on the minds of women, both urban and rural background is scrutinised separately.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Māori and community news constructions of Meningococcal B: the promotion of a moral obligation to vaccinate

open access: yes, 2007
News media communicate various risks of disease, showcase medical breakthroughs and disseminate texts that both reflect and renegotiate shared cultural understandings of health and illness. Little is known about the role of Māori and community news media
Groot, Shiloh Ann Maree   +5 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

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