Results 71 to 80 of about 1,861,055 (314)

Social media as a health resource [Elektronisk resurs] : A salutogenic perspective

open access: yes, 2018
This chapter explores the consequences of pathogenic notions of health in terms of a focus on risk and disease. A salutogenic perspective is an alternative way of discussing young people, social media, and health.
Quennerstedt, Mikael,
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

A clinical comparison of a digital versus conventional design methodology for transtibial prosthetic interfaces

open access: yesScientific Reports
A transtibial prosthetic interface typically comprises a compliant liner and an outer rigid socket. The preponderance of today’s conventional liners are mass produced in standard sizes, and conventional socket design is labor-intensive and artisanal ...
Duncan R. C. Lee   +11 more
doaj   +1 more source

Effectiveness of just-in-time adaptive interventions for improving mental health and psychological well-being: a systematic review and meta-analysis

open access: yesBMJ Mental Health
Question The rising prevalence of mental health conditions and a global treatment gap demand new solutions that address symptoms and foster psychological well-being.
Sebastian Scherr   +2 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Gas Man derived compartmental and Lerou physiological model vs Lu et al clinical data for desflurane

open access: yes, 2014
The described work is part of the Health Sciences Center Media Services Graphic Arts Poster series; the works have been created in cooperation with faculty, staff and students in an effort to inform and educate the public about related health and medical
Sadean, Mihai R.   +1 more
core  

Interactive social media interventions to promote health equity: an overview of reviews

open access: yes, 2016
Introduction: Social media use has been increasing in public health and health promotion because it can remove geographic and physical access barriers. However, these interventions also have the potential to increase health inequities for people who do ...
J. Petkovic   +4 more
core   +1 more source

Burden and Determinants of Syndromic Sexually Transmitted Infections among Key Populations on Combined HIV Prevention in Five Cameroonian Cities: A Cross-Sectional Study

open access: yesHealth Research in Africa
Introduction. Sexually transmitted infections (STIs) remain a major burden among key populations in sub-Saharan Africa, yet data among men who have sex with men (MSM) and female sex workers (FSW) receiving combined HIV prevention including pre-exposure ...
Nkoro Ombede Grace Anita   +13 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

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