Results 101 to 110 of about 12,036,737 (367)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Recruiting people with selected citizenships for the health interview survey GEDA Fokus throughout Germany: evaluation of recruitment efforts and recommendations for future research

BMC Medical Research Methodology
Background Germany is the second most common country of immigration after the US. However, people with own or familial history of migration are not represented proportionately to the population within public health monitoring and reporting.
Carmen Koschollek, Beate Gaertner, Julia Geerlings, Ronny Kuhnert, Elvira Mauz, Claudia Hövener   +5 more
doaj   +1 more source

Inequalities in the Access to Health Services Among Older Migrants: Evidence From the China Migrant Dynamic Monitoring Survey [PDF]

, 2023
Chengxu Long, Fangfei Chen, Yisheng Ye, Lü Ji, Xinyin Xu, Shangfeng Tang   +5 more
openalex   +1 more source

Wearable Sensors for Remote Health Monitoring

Italian National Conference on Sensors, 2017
Life expectancy in most countries has been increasing continually over the several few decades thanks to significant improvements in medicine, public health, as well as personal and environmental hygiene.
Sumit Majumder, Tapas K. Mondal, M. Jamal Deen, S. Evoy, B. Fidan   +4 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Background and Methodology of the 2024 annual survey from the panel ‘Health in Germany’ by the Robert Koch Institute [PDF]

Journal of Health Monitoring
Background: As the RKI’s new data collection infrastructure, the RKI Panel ‘Health in Germany’ offers the opportunity to regularly collect primary data on topics relevant to public health among the population in Germany (survey mode: online – CAWI and ...
Johannes Lemcke, Stefan Damerow, Tim Kuttig, Ilter Öztürk, Stefan Albrecht, Tobias Heller, Sabine Born, Matthias Wetzstein, Jennifer Allen   +8 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

SCIBORG: Analyzing and Monitoring LMJ Facility Health and Performance Indicators

, 2020
Jean-Philippe Airiau, Vincent Denis, Pauline Fourtillan, Chloé Lacombe, Sébastien Vermersch   +4 more
openalex   +1 more source

Mobile-health for recording and monitoring nutritional status of toddler during COVID-19 pandemic era [PDF]

, 2022
Atika Hendryani, Vita Nurdinawati, Ernia Susana, Ma’murotun Ma’murotun, Didit Damayanti   +4 more
openalex   +1 more source