Results 151 to 160 of about 12,036,737 (367)
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Flexible Sensors for Battery Health Monitoring. [PDF]
Wang X +13 more
europepmc +1 more source
Naïve Bayes as a Probabilistic Tool for Monitoring the Health Status of Chronic Patients
Laura Martínez-Marquina +3 more
openalex +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Developments in smoking behaviour during the transition from adolescence to young adulthood. Results of the KiGGS cohort [PDF]
Elvira Mauz +6 more
doaj +1 more source
Wearable Sensors for Human Health Monitoring and Analysis. [PDF]
Scano A, Re R, Perego P, Mastropietro A.
europepmc +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Recent Advances in Wearable Biosensors for Human Health Monitoring. [PDF]
Xian X.
europepmc +1 more source

