Results 91 to 100 of about 214,176 (243)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Visualizing the Interpretation of a Criteria-Driven System That Automatically Evaluates the Quality of Health News: Exploratory Study of 2 Approaches. [PDF]

JMIR AI, 2022
Liu X, Alsghaier H, Tong L, Ataullah A, McRoy S.   +4 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Desensitization to Fear-Inducing COVID-19 Health News on Twitter: Observational Study. [PDF]

JMIR Infodemiology, 2021
Stevens HR, Oh YJ, Taylor LD.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Postcards from the edge [PDF]

Journal of Primary Health Care, 2020
Katharina Blattner, Carol Atmore, Sara Gordon, Margaret Fielding, Robin Chan, Wilson Mitchell, Emma Davey, Philippa Cross, Brendan Marshall, Clare Ward, Rory Miller   +10 more
doaj  

Communication from the news of the birth of a child with Down Syndrome: the effect of a discouraging prediction

Revista Facultad Nacional de Salud Pública, 2011
Objective: to know how health workers give the news of the birth of a child with Down syndrome (ds). Methodology: qualitative, ethnographic. Involved 20 mothers and one grandmother were semistructured interviews and field observations.
Gloria M. Alcaraz L, Miriam Bastidas A
doaj  

The Benefits, Factors, and Barriers Faced in the Implementation of Digital National Early Warning Score in Hospitals: A Scoping Review

Journal of Nursing Practice
Digital National Early Warning Score (NEWS) is a system designed to detect early clinical deterioration in patients by monitoring vital parameters using digital technology. The implementation of Digital NEWS in hospitals is increasingly gaining attention
Fricilia Noya, Yanny Trisyani, Etika Emaliyawati   +2 more
doaj   +1 more source

A New Deal in Health Education

American Journal of Public Health and the Nations Health, 1934
THE other day I heard a man remark that undoubtedly the last stand of " rugged individualism" in this country would be in New York City among its. 1,200 separate, independent social and health agencies. He hoped we were on the way toward communizing the industrialists, but feared that it would be a long and tedious task to socialize the social workers.
openaire   +3 more sources