Results 141 to 150 of about 1,604,769 (359)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Fatores associados à qualidade de vida de idosos que frequentam uma unidade de saúde do Distrito Federal

Revista Brasileira de Geriatria e Gerontologia
OBJETIVO: Identificar os fatores associados à qualidade de vida de idosos que frequentam uma unidade de saúde de Ceilândia-DF. MÉTODO: Pesquisa de abordagem quantitativa do tipo descritiva com delineamento transversal, realizada com 277 idosos, por ...
Marina Morato Stival, Luciano Ramos de Lima, Silvana Schwerz Funghetto, Alessandro Oliveira Silva, Diana Lúcia Moura Pinho, Margô Gomes de Oliveira Karnikowski   +5 more
doaj   +1 more source

Nutritional status of elderly assisted in primary care and their relationship with social determinants of health

, 2023
Geórgia Ferreira da Silva Bandeira, RAFAEL DA SILVEIRA MOREIRA, Vanessa de Lima SILVA   +2 more
openalex   +1 more source

The Best of Times, the Worst of Times: Understanding Pro-cyclical Mortality [PDF]

A growing literature documents cyclical movements in mortality and health. We examine this pattern more closely and attempt to identify the mechanisms behind it.
Ann Huff Stevens, Douglas L. Miller, Marianne E. Page, Mateusz Filipski   +3 more
core  

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Neutralizing antibodies to SARS-CoV-2 Omicron variant after 3 ^rd mRNA vaccination in health care workers and elderly subjects and response to a single dose in previously infected adults [PDF]

, 2021
Anu Haveri, Anna Solastie, Nina Ekström, Pamela Österlund, Hanna Nohynek, Tuomo Nieminen, Arto A. Palmu, Merit Melin   +7 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

The Effects of State Medicaid Policies on the Dynamic Savings Patterns of the Elderly [PDF]

States have considerable flexibility in determining Medicaid policies such as financial eligibility criteria, subsidies for home- and community-based services, and reimbursements rates to skilled nursing facilities, among other things.
Donna Gilleskie, Lara Gardner
core  

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Plan management of elderly care: perceptions from health and social assistance professionals regarding the challenges and possibilities of overcoming

, 2021
Eliana Yoko Yagi
openalex   +1 more source