Results 121 to 130 of about 597,845 (266)

Impact of polypharmacy on oral health in the elderly: challenges and management. [PDF]

Front Dent Med
Halasabalu Kalgeri S, Bheemasamudra Balaraj S, Shivakumar AT, G Doddawad V, Basapur Vijayakumar D, H S S, Aradya A, Mysore Shankar P, Doggalli N, Bharadwaj SR.   +9 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Does Family Doctor Contracting Improve the Health of the Elderly: An Empirical Study from Beijing, China. [PDF]

J Multidiscip Healthc
Lv B, Wang Z, Meng K.
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Privacy, Security & Governance Frameworks for AI-Powered Wearable Internet of Health Things in Elderly Care: A Comprehensive Review. [PDF]

Risk Manag Healthc Policy
Dharmansyah D, Rahayuwati L, Pramukti I, Mutyara K.   +3 more
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Value-based health care in mobile integrated health for acute elderly care: A qualitative study of health care professionals in Finland. [PDF]

Health Care Manage Rev
Wang F, Pekanoja S, Ahokangas P, Jansson M.   +3 more
europepmc   +1 more source

Anthropometrically estimated calf muscle circumference is a marker for early detection of muscle mass decline in older adults: Second report

The Journal of Nutrition, Health and Aging
Ryo Sato, Yohei Sawaya, Tamaki Hirose, Takahiro Shiba, Lu Yin, Shuntaro Tsuji, Tomohiko Urano   +6 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

The social integration-health nexus for elderly migrants: evidence from China migrants dynamic survey. [PDF]

BMC Geriatr
Wang Q, Wen J, Yao L, Mu X, Zou J.
europepmc   +1 more source