Results 231 to 240 of about 1,604,769 (359)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Prevalence of Dysphagia and Its Health Implications Among Elderly Residents in Long-Term Care Facilities in the Liguria Region (Italy): An Observational Cohort Study. [PDF]

Nutrients
Formisano E, Di Cino E, Nicosia E, Pasta A, Paccione G, Sukkar AA, Pisciotta L, Sukkar SG.   +7 more
europepmc   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Concern for the Health of Ethiopia's Elderly Population: A Call for a Comprehensive Geriatric Medicine Strategy. [PDF]

Ethiop J Health Sci
Dode WW, Teso SD.
europepmc   +1 more source

Meta-analysis of qualitative studies examining the experiences of elderly patients with cardiovascular diseases in using digital health technologies

Zhao Ruiyan
openalex   +1 more source

Most common health problems of elderly in the opinion of health sciencesstudents in Poland, Belarus and Greece

, 2016
Mateusz Cybulski, Elżbieta Krajewska-Kułak, Paweł Sowa, A. Shpakau, Eleni Theodosopoulou, A Chadzopulu   +5 more
openalex   +1 more source

Track: Health of the Elderly [PDF]

European Journal of Public Health, 2006
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Breaking the Cycle: Enhancing Cardiovascular Health in the Elderly Through Group Exercise. [PDF]

Life (Basel)
Bilajac L, Marinović Glavić M, Kristijan Z, Matea B, Juraga D, Jelaković A, Rukavina T, Vasiljev V, Jelaković B.   +8 more
europepmc   +1 more source

Prevention of Obesity in The Elderly Through Health Promotion Interventions: Literature Review

Miranda Gracia Salsabila, Ernawaty Ernawaty, I. Fauziah   +2 more
openalex   +1 more source