Results 121 to 130 of about 840,042 (282)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

El láser ¿motivación o realidad para el estudio de Física por los estudiantes de las Ciencias para la Salud?

Revista Cubana de Investigaciones Biomédicas
Se realizó este estudio para que sirviera de instrumento de trabajo y de fuente de consulta a los estudiosos e interesados en el tema. La palabra láser es una sigla de las palabras inglesas light amplification by stimulated emission of radiation ¿qué ...
José E. García González, Fernando de la C. Martínez Rodríguez   +1 more
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The Fusion Mechanism and Prospective Application of Physics-Informed Machine Learning in Bridge Lifecycle Health Monitoring

Infrastructures
Bridge health monitoring is crucial for ensuring the safety and durability of infrastructure. In traditional methods, physics-based models have high interpretability but are difficult to handle complex nonlinear problems, while purely data-driven machine
Jiaren Sun, Jiangjiang He, Guangbing Zhou, Jun Yang, Xiaoli Sun, Shuai Teng   +5 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Physical Information-Guided Kolmogorov–Arnold Networks for Battery State of Health Estimation

Energies
Against the backdrop of the rapid development of the energy internet, the role of energy storage systems in grid stability, energy balance, and renewable energy integration has become increasingly important.
Zeye Liu, Songtao Ye, Feifei Cui, Yu Ma
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Physical Health [PDF]

Journal of Intellectual Disability Research, 2019
  +4 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

50^th birthday of Christian von Ferber

Condensed Matter Physics, 2011
On May 15, 2011 Christian von Ferber - member of the Editorial Board of "Condensed Matter Physics" and renowned expert in the fields of soft matter physics and complex systems - celebrated his 50th birthday.
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