Results 111 to 120 of about 14,999,889 (355)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Ethical approaches to family planning in Africa [PDF]

open access: yes
Africa has historically provided the geographical flashpoint of ethical issues relating to family planning programs. Until recently in Sub-Saharan Africa, advocacy of family planning by non-Africans was unacceptable and by Africans politically ...
Newman, K., Sai,F. T.
core  

The need to improve implementation and use of lifestyle surveillance systems for planning prevention activities: an analysis of the Italian Regions [PDF]

open access: yes, 2016
Objectives: To describe the level of use of lifestyle surveillance systems in Italy and to identify predictors of their use by the Italian Regions for planning and monitoring purposes.
D'Andrea, Elvira   +6 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

O pacto pela saúde e o fundo municipal de saúde de Várzea Paulista Health pact and the municipal health fund of Várzea Paulista

open access: yesSaúde e Sociedade, 2009
A reestruturação do Fundo Municipal de Saúde de Várzea Paulista teve como objetivos: reorganizar o orçamento municipal de acordo com o Pacto pela Saúde, integrar ações do planejamento e gestão orçamentário-financeira, atualizar a legislação municipal e ...
Luís Fernando Nogueira Tofani   +2 more
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Economic Tools for Rural Health Planning [PDF]

open access: yes
The full contribution of hospitals, clinics, pharmacies, etc to the rural economy often goes unrecognized. Quality health services are needed to attract businesses, and required for rural populations with a high proportion of elderly.
Doeksen, Gerald A.
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The Vital Link: Generalist clinical discipline in a world of health care markets and strategic planning

open access: yesSouth African Family Practice, 1990
No abstract available.
Nigel C.H. Stott
doaj   +1 more source

Why Family Planning and Reproductive Health are Critical to the Well-Being of Youth [PDF]

open access: yes, 2009
An unprecedented number of young people are entering their reproductive years, most of whom live in the developing world. U.S. policy makers should assist in effortS to ensure that youth worldwide are able to make informed decisions about their sexuality

core  

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