Results 121 to 130 of about 220,169 (313)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Using GIS to Identify Priority Sites for Colorectal Cancer Screening Programs in Texas Health Centers [PDF]

, 2023
F. Benjamin Zhan, Yanyan Liu, Mei Yang, Nicole Kluz, Todd A. Olmstead, Jenny S. Spencer, Navkiran K. Shokar, Roxana L. Cruz, Michael Pignone   +8 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Assessing the contributions of an urban population health initiative to shift political priority towards cardiovascular health: three case studies from Brazil, Mongolia and Senegal [PDF]

Jasmina Saric, Ann Aerts, Malick Anne, Joseph Barboza, Johannes Boch, Naranjargal Dashdorj, D McGhie, Adela Santana, Jason T. Shellaby, Suely Miya Shiraishi Rollemberg, Mariana Silveira, Peter Steinmann, Daniel Cobos Muñoz   +12 more
openalex   +1 more source

Perinatal mental health around the world: priorities for research and service development in Italy [PDF]

, 2019
Pietro Grussu, Ilaria Lega, Rosa Maria Quatraro, Serena Donati   +3 more
openalex   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Emergence of antibiotic resistance: A global public health and a political priority

, 2018
Saurabh RamBihariLal Shrivastava, PrateekSaurabh Shrivastava   +1 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Perceived Healthcare Priorities, Barriers, and Preferences When Selecting Private or Governmental Healthcare Services Among a Sample of University Affiliates from Saudi Arabia

Patient Preference and Adherence
Ibrahim M Gosadi, Mohammad A Jareebi Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi ArabiaCorrespondence: Ibrahim M Gosadi, Department of Family and Community Medicine, Faculty of Medicine, Jazan ...
Gosadi IM, Jareebi MA
doaj  

Bacterial resistance to antibiotics in France : a public health priority

, 2000
H Aubry Damon, Jean Carlet, Patrice Courvalin, J C Desenclos, J Drucker, Didier Guillemot, Vincent Jarlier, B. Régnier, Benoı̂t Schlemmer   +8 more
openalex   +1 more source