Results 121 to 130 of about 1,128,412 (358)

Covering Kids & Families Evaluation: Expectations of Sustainability: What Do CKF Grantees and State Officials Predict Will Happen Once RWJF Funding Ends? [PDF]

open access: yes, 2005
Based on a survey of CKF state grantees and Medicaid and Children's Health Insurance Program officials, examines prospects for continuing efforts to increase enrollment, factors contributing to survival, alternative funding sources, and ...
Beth Stevens, Sheila D. Hoag
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The Performance Improvement Imperative: Utilizing a Coordinated, Community-Based Approach to Enhance Care and Lower Costs for Chronically Ill Patients [PDF]

open access: yes, 2012
Proposes principles for federal leadership and a community-level strategy for improving healthcare performance for high-cost patients as a way to curb health spending.

core  

Establishing patient-partner priorities within the primary and integrated health care innovations network in Canada [PDF]

open access: gold, 2022
Jamie DeMore   +10 more
openalex   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Decentralization and Public Delivery of Health Care Services in India [PDF]

open access: yes
This paper examines delivery of public health care services in India, in the broader context of decentralization. It provides an overview of the basic features and recent developments in intergovernmental fiscal relations and accountability mechanisms ...
Singh, Nirvikar
core   +1 more source

What are the research priorities for strengthening public health emergency preparedness and response in Africa? [PDF]

open access: gold, 2023
Obinna Onwujekwe   +9 more
openalex   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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