Results 121 to 130 of about 1,032,633 (361)

127:oral Withdrawing or withholding treatments in health care rationing decisions: an interview study

open access: yesBMJ Global Health, 2022
Lars Sandman   +3 more
doaj   +1 more source

Gender Matters: An Analysis of the 2012-2013 Texas State Budget [PDF]

open access: yes, 2012
Gender Matters focuses on the impacts of Texas fiscal policy on the health, safety, education and economic security of women and girls. The report, researched by the Center for Public Policy Priorities for the Dallas Women's Foundation, identifies ...

core  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Perceived Healthcare Priorities, Barriers, and Preferences When Selecting Private or Governmental Healthcare Services Among a Sample of University Affiliates from Saudi Arabia

open access: yesPatient Preference and Adherence
Ibrahim M Gosadi, Mohammad A Jareebi Department of Family and Community Medicine, Faculty of Medicine, Jazan University, Jazan, Saudi ArabiaCorrespondence: Ibrahim M Gosadi, Department of Family and Community Medicine, Faculty of Medicine, Jazan ...
Gosadi IM, Jareebi MA
doaj  

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Educational Priorities of Self-Care Based on Needs Assessment of Household Health Ambassadors [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Self-care is recognized as a fundamental approach in the field of providing, maintaining, and promoting health in individuals, families, and society.
Fatemeh Jafarian   +4 more
doaj  

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