Results 121 to 130 of about 12,227,603 (310)

127:oral Withdrawing or withholding treatments in health care rationing decisions: an interview study

BMJ Global Health, 2022
Lars Sandman, Liam Strand, Gustav Tinghög, Ann-Charlotte Nedlund   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

104:oral Should the assessment of severity have a ‘pandemic-premium’?

BMJ Global Health, 2022
Lars Sandman
doaj   +1 more source

A 10-Step Method for Fair Priority-Setting Processes: A Qualitative Case Study from Zanzibar

Health Systems & Reform
Health systems worldwide face challenges in managing resource scarcity, necessitating systematic and fair approaches to prioritize essential health services.
Omar Mwalim, Sanaa Said, Subira Suleiman, Fatma Bakar, Haji Khamis, Dhameera Mohammed, Zuhura Amour, Omar Mussa, Abdulmajid Jecha, Abdul-Latif Haji, Ole F. Norheim, Ingrid Miljeteig, Austen Davis, Peter Hangoma, Kjell Arne Johansson   +14 more
doaj   +1 more source

Systematic review for the development of a pharmaceutical and medical products prioritization framework

Journal of Pharmaceutical Policy and Practice, 2019
Objective To identify and analyze the criteria, approaches, and conceptual frameworks, used for national/international priority setting. Data sources We performed a search of the main biomedical databases (Medline/PubMed, Embase, Centre for Reviews and ...
Alberto Frutos Pérez-Surio, Mercedes Gimeno-Gracia, Ma. Aránzazu Alcácera López, Ma. Asunción Sagredo Samanes, Ma. del Puerto Pardo Jario, Ma. del Tránsito Salvador Gómez   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Priorities and programs

, 1984
An outline of the Priorities and programs of the Northern Territory Department of Health in the ...

core  

WHO compendium of innovative health technologies for low-resource settings: 2021: COVID-19 and other health priorities

, 2021
xxvi, 54 p.This publication presents the 2021 WHO Compendium of Innovative Health Technologies for Low-Resource Settings, focusing on technologies relevant to COVID-19 and other public health priorities.
World Health Organization
core