Results 121 to 130 of about 280,483 (314)

Center on Budget and Policy Priorities

open access: yes, 2013
The Center on Budget and Policy Priorities is a nonpartisan research organization and policy institute that conducts research and analysis on a range of government policies and programs, with an emphasis on those affecting low and moderate income people.
Center on Budget and Policy Priorities
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Bacillus anthracis Bioterrorism Research Priorities for Public Health Response [PDF]

open access: yes
This meeting provided a forum for 132 representatives from the Department of Health and Human Services (Centers for Disease Control and Prevention (CDC), Food and Drug Administration (FDA), and National Institutes of Health (NIH)), Environmental ...

core  

A Delphi study to identify research priorities for the therapy professions in Northern Ireland

open access: yes, 2011
A study by the University of Ulster, funded by Health and Social Care Research and Development Division of the Public Health Agency, enabled members of six Allied Health Professions (AHPs) to express opinions on research needs within their areas of ...
Public Health Agency
core   +1 more source

Research priorities in environmental health

open access: yesBMJ, 1999
Education and debate pp 1678-93 Environmental issues are often high up on the political agenda. However, environmental health aspects tend to receive a lower priority. When conflicts of interest occur with other environmentalconcerns this may result in negative consequences for public health.
openaire   +3 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Stakeholders’ Involvement in Health Technology Assessment in Kazakhstan, Poland and Bulgaria

open access: yesPatient Preference and Adherence
Lyazzat Kulembekova,1 David Hailey,2 Maksut Kulzhanov,1 Adlet Tabarov,3 Svetlin Georgiev,4 Magdalena Jaworzynska,5 Antoniya Yordanova Yanakieva,4 Lyazzat Kosherbayeva1,6 1Health Policy and Management Department, Asfendiyarov Kazakh National Medical ...
Kulembekova L   +7 more
doaj  

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