Results 191 to 200 of about 1,128,412 (358)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Community-driven mental health priorities for immigrant youth in Alberta. [PDF]

Front Health Serv
Naqvi SF, Amarbayan M, Dimitropoulos G, Zwicker J, Santana MJ.   +4 more
europepmc   +1 more source

Priority Setting for Health: A Critique of Alternative Models: Report to the Population Health Division Department of Health and Aged Care

, 2017
Leonie Segal, Ying Chen
openalex   +1 more source

The Hungarian government has made national health a priority: a reply [PDF]

, 2018
Zoltán Ónodi-Szűcs
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Frameworks for Priority Setting in Health and Social Care

, 2019
Marissa Collins, Neil McHugh, Rachel Baker, Alec Morton, Lucy Frith, Keith Syrett, Cam Donaldson   +6 more
openalex   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Mapping political commitments: Analysing health priorities in Indian election manifestos. [PDF]

J Family Med Prim Care
Rajeev BR, Ram A, Nivedhya R, Das SS.
europepmc   +1 more source

Strategy at the crossroads: The case of the navy hospital ships [PDF]

We examine the state of knowledge in the defense literature on the use of military medical humanitarian assistance missions and examine their implications for navy hospital ships.
Richter, Anke, Webb, Natalie J
core   +1 more source

Analysis of the priority of roles performed by health educators in charge of health promotion programs at community health centers

, 2014
Seung Hee Choi, Myung Kim
openalex   +2 more sources