Results 231 to 240 of about 1,128,412 (358)

Financial Distress and Depressive Symptoms among African American Women: Identifying Financial Priorities and Needs and why it Matters for Mental Health [PDF]

, 2012
Angelica JoNel Starkey, Christopher R. Keane, Martha Ann Terry, John Marx, Edmund M. Ricci   +4 more
openalex   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Redefining health priorities: Sub-Saharan Africa's new frontier in disease burden. [PDF]

J Glob Health
Zerfu TA, Tareke AA, Biadgilign S.
europepmc   +1 more source

Health needs as a priority of local authorities in Poland based on the example of implementation of health policy cancer programmes [PDF]

, 2016
Anna Augustynowicz, Aleksandra Czerw, Andrzej Deptała   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Need for a Travel Medicine Diploma in Saudi Arabia: Addressing National and Global Health Priorities. [PDF]

J Epidemiol Glob Health
Sheerah HA, Brazanji NA, Al-Zahrani FA, Muammar NB, AlBassam AM, Alfaya MA, Aldosaimani A, Alshahrani NZ, Alosaimi M, Almaziad S, AlZunitan MA, Farahat FM, Alshamrani MM.   +12 more
europepmc   +1 more source

Setting research priorities for maternal, newborn and child health, sexual and reproductive health and nutrition in Afghanistan: an application of the Child Health and Nutrition Research Initiative methodology [PDF]

T. K. Majumdar, Emily C Keats, Hana Tasic, Sama El Baz, David H. Peters, Najibullah Safi, Hannah Tappis, Nadia Akseer   +7 more
openalex   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Regional health priorities for dementia: a roadmap for the Western Pacific. [PDF]

Lancet Reg Health West Pac
Timmins HC, Mok VCT, Kim SH, Shahrizaila N, Sung JY, Sobue G, Agustini S, Ward S, Anstey KJ, Talbot DL, Mazumder S, Tu S, Tan RH, Shin-Yi Lin C, O'Callaghan C, Michaelian JC, Jeon YH, Foxe D, Naismith SL, Piguet O, Ahmed R, Devenney E, Park SB, Kiernan MC.   +23 more
europepmc   +1 more source

Cardiovascular Health—A Workplace Priority [PDF]

AAOHN Journal, 2002
openaire   +2 more sources