Results 231 to 240 of about 1,128,390 (308)

One Health Priorities: Advancing Veterinary Public Health in Latin America and the Caribbean. [PDF]

Pathogens
Rocha F, Sibim AC, Molina-Flores B, Chiba de Castro WA, Kmetiuk LB, Alves RV, Dos Santos ALS, Moreno MC, Faccini-Martínez ÁA, Cediel NM, Biondo AW, Cosivi O, Vigilato MAN.   +12 more
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Exploring the nurse-patient relationship in caring for the health priorities of older adults: qualitative study. [PDF]

BMC Nurs
Shaban M, Mohammed HH, Gomaa Mohamed Amer F, Shaban MM, Abdel-Aziz HR, Ibrahim AM.   +5 more
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Focusing field epidemiology training on national health priorities in Papua New Guinea: consultative prioritization, from health workers to policy-makers. [PDF]

Western Pac Surveill Response J
Housen T, Ropa B, Flint J, Merritt T, Hammersley-Mather R, Pukienei A, Dagina R, Peni B, Pogo M, Durrheim DN.   +9 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Launching the Global Health Network Middle East and North Africa Regional Network: A Path to Promote the Region's Global Health Research Presence and Build Unity and Collaboration Towards Tackling Regional Public Health Priorities. [PDF]

Healthcare (Basel)
Alrubaie M, Tarekegne RA, Rahman S, Manikandan P, Zeeshan S, AlBada M, Lang T, Takshe AA, Alkhaldi M.   +8 more
europepmc   +1 more source