Results 51 to 60 of about 1,032,633 (361)

An Integrated Approach to the delivery of Child Mental Health Services [PDF]

, 2005
While these documents contain very welcome recommendations for the well being of children, they touch upon the issues of child mental health only indirectly.
Kapur, Malavika
core  

occumb: An R package for site occupancy modeling of eDNA metabarcoding data

Population Ecology, EarlyView.
This study introduces a new R package, occumb, for the convenient application of site occupancy modeling using environmental DNA (eDNA) metabarcoding data. We outline a data analysis workflow, including data setup, model fitting, model assessment, and comparison of potential study settings based on model predictions, all of which can be performed using
Keiichi Fukaya, Yuta Hasebe
wiley   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A Call for Change: The 2011 Commonwealth Fund Survey of Public Views of the U.S. Health System [PDF]

, 2011
Presents survey findings about the public's experiences with access to health care, care coordination, cost and administrative burdens, and health services delivery; their concerns; and priorities for system reform by income, insurance status, and ...
Ashley-Kay Fryer, Cathy Schoen, Kristof Stremikis   +2 more
core  

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Covering Kids & Families Evaluation: Expectations of Sustainability: What Do CKF Grantees and State Officials Predict Will Happen Once RWJF Funding Ends? [PDF]

, 2005
Based on a survey of CKF state grantees and Medicaid and Children's Health Insurance Program officials, examines prospects for continuing efforts to increase enrollment, factors contributing to survival, alternative funding sources, and ...
Beth Stevens, Sheila D. Hoag
core  

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

A 10-Step Method for Fair Priority-Setting Processes: A Qualitative Case Study from Zanzibar

Health Systems & Reform
Health systems worldwide face challenges in managing resource scarcity, necessitating systematic and fair approaches to prioritize essential health services.
Omar Mwalim, Sanaa Said, Subira Suleiman, Fatma Bakar, Haji Khamis, Dhameera Mohammed, Zuhura Amour, Omar Mussa, Abdulmajid Jecha, Abdul-Latif Haji, Ole F. Norheim, Ingrid Miljeteig, Austen Davis, Peter Hangoma, Kjell Arne Johansson   +14 more
doaj   +1 more source