Results 51 to 60 of about 993,777 (361)

Network topology drives population temporal variability in experimental habitat networks

Population Ecology, EarlyView.
Habitat patches connected by dispersal pathways form habitat networks. We explored how network topology affects population outcomes in laboratory experiments using a model species (Daphnia carinata). Central habitat nodes in complex lattice networks exhibited lower temporal variability in population sizes, suggesting they support more stable ...
Yiwen Xu, J. Angus Webb, William D. Bovill, Elise L. King   +3 more
wiley   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

FEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi, WanTing Kong, Camille Blériot, Joel T. Haas   +3 more
wiley   +1 more source

The interaction between policy and education using stroke as an example [PDF]

, 2008
This paper discusses the interaction between healthcare policy at the European, UK and Scottish levels and the funding of education that underpins specific health policy priorities.
Aiken, Aiken, Alberts, Booth, Byford, Chapman, Chapman, Charlton, Corea, Demaerschalk, Duncan, Elkins, Fang, Glen, Glen, Hacke, Hoban, LaMonte, Langhorne, Levine, Lindley, Lorraine N. Smith, Louise E. Craig, Matchar, Sandercock, Shiell, Stone, Warlow, Warlow   +28 more
core   +1 more source

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

A Call for Change: The 2011 Commonwealth Fund Survey of Public Views of the U.S. Health System [PDF]

, 2011
Presents survey findings about the public's experiences with access to health care, care coordination, cost and administrative burdens, and health services delivery; their concerns; and priorities for system reform by income, insurance status, and ...
Ashley-Kay Fryer, Cathy Schoen, Kristof Stremikis   +2 more
core  

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

The Next WHO Director-General’s Highest Priority: a Global Treaty on the Human Right to Health [PDF]

, 2016
Amidst the many challenges facing the next WHO Director-General, the new WHO head should find WHO’s foremost priority in its most important constitutional pillar: the right to health. The centerpiece of this endeavor should be leadership on the Framework
Buss, Paulo, Chowdhury, Mushtaque, Friedman, Eric A., Gostin, Lawrence O., Grover, Anand, Heywood, Mark, Kanchanachitra, Churnrurtai, Leung, Gabriel, MacKay, Judith, Matsoso, Precious, Mogedal, Sigrun, Mukherjee, Joia S., Omaswa, Francis, Periago, Mirta Roses, Phumaphi, Joy, Reddy, K. Srinath, Thomas, Joe, Tomori, Oyewale, Were, Miriam, Zewdie, Debrework   +19 more
core   +2 more sources

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Treatment decision-making process after an anterior cruciate ligament injury: patients’, orthopaedic surgeons’ and physiotherapists’ perspectives

BMC Musculoskeletal Disorders, 2022
Objective To investigate the treatment decision-making process after an anterior cruciate ligament (ACL) injury from patients’, orthopaedic surgeons’ and physiotherapists’ perspectives. Methods The study is a part of the NACOX study, which is designed to
Hanna Tigerstrand Grevnerts, Barbro Krevers, Joanna Kvist   +2 more
doaj   +1 more source

Health Care Opinion Leaders' Views on Health Reform, Implementation, and Post-Reform Priorities [PDF]

, 2010
Presents survey results on healthcare experts' views on the comprehensive health reform law enacted in March 2010, including premium subsidies, new insurance market rules, and alternative payment methods; implementation challenges; and long-term ...
Karen Davis, Kristof Stremikis, Rachel Nuzum   +2 more
core