Results 101 to 110 of about 2,476,569 (314)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Evaluating the effectiveness of surgical detoxification treatment of inflammatory and vascular eye diseases

Oftalʹmologiâ, 2016
Purpose: to study the advantages and the efficiency of improvement of the surgical detoxification in patients with inflammatory and vascular eye diseases.Patients and Methods.
L. P. Danilova, V. V. Egorov, G. P. Smoljakova, L. P. Emanova, D. A. Povaljaeva   +4 more
doaj   +1 more source

Emerging communities of child-healthcare practice in the management of long-term conditions such as chronic kidney disease: Qualitative study of parents' accounts [PDF]

, 2014
Background: Parents of children and young people with long-term conditions who need to deliver clinical care to their child at home with remote support from hospital-based professionals, often search the internet for care-giving information.
A Macfadyen, AL May, Andy Hall, B Flyvbjerg, BL Patterson, C Clarke, C Jaye, C Pope, C Tuffrey, Darzi, DJ Ward, DOH, E Ahmann, E Coakes, E Lesser, E Wenger, E Wenger, E Wenger, G Crow, H Roberts, I Falk, Ian Carolan, ICT, J Betancourt, J Collier, J Ellins, J Flora, J Lathlean, J Lave, KL Whyte, L Lowes, L Thrysoe, M Dixon-Woods, M Lewis, MD Sinha, MRC, Office for National Statistics (2013) National-Statistics-Online, P Griffiths, R Lazarus, S Bowles, S Marr, SDCNSRN Sullivan-Bolyai, T Egan, T Ferguson, T Rapley, Trish Smith, V Swallow, V Swallow, V Swallow, V Swallow, V Swallow, V Swallow, V Swallow, V Swallow, Veronica M Swallow, VM Swallow, VM Swallow, VM Swallow   +57 more
core   +3 more sources

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Promptology: Enhancing Human–AI Interaction in Large Language Models

Information
This study investigates the integration of generative AI in higher education and the development of the SPARRO framework, a structured approach to improving human–AI interaction in academic settings.
Phillip Olla, Lauren Elliott, Mustafa Abumeeiz, Karen Mihelich, Joshua Olson   +4 more
doaj   +1 more source

Stigma and treatment of eating disorders in Ireland: healthcare professionals' knowledge and attitudes [PDF]

, 2015
Objectives: This study examines aspects of health professionals’ knowledge and attitudes about eating disorders (EDs) , which might impede the effective detection or treatment of EDs in Ireland.
McNamara, N, McNicholas, F, O'Connor, C, O'Hara, L   +3 more
core   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source

Health professionals prefer to communicate risk-related numerical information using "1-in-X" ratios [PDF]

, 2017
Previous research showed that format effects such as the “1-in-X” effect – whereby “1-in-X” ratios lead to a higher perceived probability than “N-in-N*X” ratios – alter perceptions of medical probabilities.
Bhatia, Sudeep, Garcia-Retamero, Rocio, Juanchich, Marie, Petrova, Dafina, Sirota, Miroslav, Walasek, Lukasz   +5 more
core   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Health Benefits of Urban Agriculture [PDF]

, 2003
Health professionals increasingly recognize the value of farm-and garden-scale urban agriculture. Growing food and non-food crops in and near cities contributes to healthy communities by engaging residents in work and recreation that improves individual ...
Anne C. Bellows, Jac Smit, Katherine Brown   +2 more
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