Results 41 to 50 of about 759,000 (267)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

The Social and Communicational Profile of Children Identified with Autism in Ethiopia

Children
Background: In Ethiopia, children identified with autism spectrum disorder (ASD) and their families face substantial challenges in obtaining timely diagnosis and appropriate services, including limited public awareness, cultural stigma, and shortages of ...
Waganesh A. Zeleke, Elleni Damtew Asfaw, Angela Lee, Alanna King, Suzzane Long   +4 more
doaj   +1 more source

Understanding the atmospheric circulations that lead to high particulate matter concentrations on the west coast of Namibia

Clean Air Journal, 2017
Atmospheric circulations play a significant role in determining the extent and impact of local and regional air pollution. The Erongo Region, located in the western part of Namibia, falls within the west coast arid zone of southern Africa, and is ...
H Liebenberg-Enslin, H Rauntenbach, R von Gruenewaldt, L Burger   +3 more
doaj   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Health outcomes in hospitalised and non-hospitalised individuals after COVID-19, an observational, cross-sectional study

Communications Medicine
Background Both hospitalised (H) and non-hospitalised (NH) individuals may have different symptoms and impairments after COVID-19. We aimed to explore symptoms, mental and physical health after initial COVID-19 for both groups of individuals and the ...
Malin Nygren-Bonnier, Anna Svensson-Raskh, Linda Holmström, Anna Törnberg, Annie Svensson, Daniel Loewenstein, Malin Regardt, Mikael Björnson, Carl Hallberg, Mike Kemani, Anita Mc Allister, Joakim Körner Gustafsson, Alexandra Halvarsson, Urban Ekman, Linda Nordstrand, Susanne Guidetti, Lena Anmyr, Maria Bragesjö, Jenny Åström Reitan, Farzaneh Badinlou, Oili Dahl, Eva Åkerman, Pär Villner, Petter Brodin, Kenneth Caidahl, Marcus Ståhlberg, Artur Fedorowski, Magnus Sköld, Michael Runold, Judith Bruchfeld, Elisabeth Rydwik   +30 more
doaj   +1 more source

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Clinical Empathy in Graduate Medical Education

Journal of the Dow University of Health Sciences, 2018
What is clinical empathy? “Empathy” is defifined as the ability to understand the other person's emotions, feelings and reactions and to communicate that understanding to the person effffectively ...
Muhammad Shahid Shamim
doaj   +2 more sources