Results 31 to 40 of about 2,136,146 (305)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Perceived social support and compliance on stay-at-home order during COVID-19 emergency in Nepal: an evidence from web-based cross-sectional study

BMC Public Health, 2023
Background After COVID-19 was declared a Public Health Emergency of International Concern by WHO, several non-pharmaceutical interventions were adopted for containing the virus. Success to which largely depend upon citizens’ compliance to these measures.
Namuna Shrestha, Reena Koju, Dirghayu K.C., Namra Kumar Mahato, Anil Poudyal, Ranjeeta Subedi, Nitisha Gautam, Anju Vaidya, Shristi Karki   +8 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Ciudades sostenibles y saludables: estrategias en busca de la calidad de vida

Revista Facultad Nacional de Salud Pública, 2016
Resumen Este artículo discute la relación que hay en los planteamientos del desarrollo sostenible y de las ciudades saludables como estrategias que surgen de la promoción de la salud.
Leonardo Salas-Zapata, Jennifer M. López-Ríos, Sergio Gómez-Molina, Diego Franco-Moreno, Eliana Martínez-Herrera   +4 more
doaj   +1 more source

Can a multi-level intervention approach, combining behavioural disciplines, novel technology and incentives increase physical activity at population-level?

BMC Public Health, 2021
Background Despite a global call for action and growing burden of non-communicable diseases (NCD) associated with physical inactivity, effective interventions to increase community-wide physical activity (PA) remain few.
Ling Chew, Isabel Tavitian-Exley, Nicole Lim, Alice Ong   +3 more
doaj   +1 more source

Progress and opportunities in lesbian, gay, bisexual and transgender health communications [PDF]

, 2003
This article describes elements of effective health communication and highlights strategies that may best be adopted or adapted in relation to lesbian, gay, bisexual, and transgender (LGBT) populations.
Drabble, Laurie A, Keatley, J., Marcelle, G.   +2 more
core   +2 more sources

Promoting Health Literacy [PDF]

Journal of the American Medical Informatics Association, 2004
This report reviews some of the extensive literature in health literacy, much of it focused on the intersection of low literacy and the understanding of basic health care information. Several articles describe methods for assessing health literacy as well as methods for assessing the readability of texts, although generally these latter have not been ...
openaire   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Indigenous youth peer-led health promotion in Canada, New Zealand, Australia, and the United States: A systematic review of the approaches, study designs, and effectiveness [PDF]

, 2018
Background: Youth peer-led interventions have become a popular way of sharing health information with young people and appear well suited to Indigenous community contexts.
Aguilera, Bauman, Bentley, Biggs, Carpenter, Cobb-Clark, Cochran, Crooks, Crouch, Eskicioglu, Fagan, Flicker, Flicker, Gracey, Harden, Harden, Harvey, Hayward, Humphery, Hunt, Huynh, Jepson, Kim, Lobo, Majumdar, Marlow, McCallum, McEwan, Medley, Merzel, Mikhailovich, Milburn, Mitschke, Moher, Montgomery, Morrow, Parker, Ronsley, Rushing, Santos, Sciacca, Smith, Snijder, Sun, Tighe, Tuhiwai Smith, Wang, Wilson   +47 more
core   +4 more sources