Results 131 to 140 of about 12,945,820 (301)
Health Promotion Through an Equity Lens
Health promotion is crucial to keeping people well and preventing illness. A major challenge is that many health promotion programs are focused on individual behaviour and do not take peoples’ unequal conditions and opportunities into account.
Rice, Wendy
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Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
ISSUE ADDRESSED: The activities and well-being outcomes from participating at Men's Sheds are the focus of a growing body of research. Although many Men's Sheds have a clear health or social philosophy, this does not always translate into health and ...
Richard Parsons +10 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Workplace health in America 2017 [PDF]
The Workplace Health in America 2017 survey is a nationally representative survey of U.S. employers describing the current state of U.S. workplace health promotion and protection programs and practices in worksites of all sizes, industries, and regions ...
core
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Applying usability testing techniques to improve a health promotion website
Issue addressed: Use of the Internet for health promotion is increasing; however the lack of published research regarding website usability suggests that health promotion websites are being developed without formal evaluation and consultation of their ...
Mummery, W. Kerry., Hinchliffe, Anetta.
core
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The national health & lifestyle surveys (SLÁN)
Department of public health medicine and epidemiology ...
Centre for Health Promotion Studies, Health Promotion Unit
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