Results 111 to 120 of about 13,221,289 (346)

Recent adverse mortality trends in Scotland: comparison with other high-income countries

BMJ Open, 2019
Objective Gains in life expectancy have faltered in several high-income countries in recent years. Scotland has consistently had a lower life expectancy than many other high-income countries over the past 70 years.
Colin Fischbacher, Gerry McCartney, Jon Minton, Julie Ramsay, Maria Kaye-Bardgett, Grant M A Wyper   +5 more
doaj   +1 more source

Electronic health records and burnout: Time spent on the electronic health record after hours and message volume associated with exhaustion but not with cynicism among primary care clinicians

J. Am. Medical Informatics Assoc., 2020
OBJECTIVES The study sought to determine whether objective measures of electronic health record (EHR) use-related to time, volume of work, and proficiency-are associated with either or both components of clinician burnout: exhaustion and cynicism ...
Julia Adler-Milstein, Wendi Zhao, Rachel Willard-Grace, Margae J. Knox, K. Grumbach   +4 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Patient Data Sharing and Confidentiality Practices of Researchers in Jordan

Risk Management and Healthcare Policy, 2019
Reema A Karasneh,1 Sayer I Al-Azzam,2 Karem H Alzoubi,2 Sahar S Hawamdeh,2 Suhaib M Muflih2 1Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan; 2Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan ...
Karasneh RA, Al-Azzam SI, Alzoubi KH, Hawamdeh SS, Muflih SM   +4 more
doaj  

Guide to the Sokol Blosser Winery Collection [PDF]

, 2015
The Sokol Blosser Winery was established more than 40 years ago as one of the earliest wineries in the Dundee Hills. Founders Susan Sokol Blosser and Bill Blosser first produced wine in the late 1970s.
Linfield College Archives
core   +1 more source

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records

Lancet psychiatry, 2021
M. Taquet, J. Geddes, M. Husain, S. Luciano, Paul J. Harrison   +4 more
semanticscholar   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Development of a minimum data set for a blockchain-based personal health records (PHRs), for patient/physician interaction in family medicine

Journal of Education and Health Promotion
BACKGROUND: The primary requirement for a capable patient health record (PHR) that can interact appropriately with the family medicine system and collect and share qualified data is a minimum data set (MDS) aligned with family medicine’s functions and ...
Mehdi Hajebrahimi, Mostafa Langarizadeh, Alireza Nikseresht   +2 more
doaj   +1 more source

SHealth: A Blockchain-Based Health System With Smart Contracts Capabilities

IEEE Access, 2020
Governments rely on collected data to analyze their citizens' health requirements and needs. Such data is usually of scattered manner gathered by several agencies and entities that fall under different business models and goals.
Manaf Zghaibeh, Umer Farooq, Najam Ul Hasan, Imran Baig   +3 more
doaj   +1 more source