Results 111 to 120 of about 11,060,200 (359)

Synthetic data generation for tabular health records: A systematic review

open access: yesNeurocomputing, 2022
Mikel Hernandez   +4 more
semanticscholar   +1 more source

Natural language processing of symptoms documented in free-text narratives of electronic health records: a systematic review

open access: yesJ. Am. Medical Informatics Assoc., 2019
OBJECTIVE Natural language processing (NLP) of symptoms from electronic health records (EHRs) could contribute to the advancement of symptom science.
Theresa A. Koleck   +3 more
semanticscholar   +1 more source

Evaluation and modification of tumor cell isolation techniques from malignant effusions for rapid drug sensitivity testing

open access: yesMolecular Oncology, EarlyView.
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef   +10 more
wiley   +1 more source

Opportunities and challenges in developing deep learning models using electronic health records data: a systematic review

open access: yesJ. Am. Medical Informatics Assoc., 2018
Objective To conduct a systematic review of deep learning models for electronic health record (EHR) data, and illustrate various deep learning architectures for analyzing different data sources and their target applications.
Cao Xiao, E. Choi, Jimeng Sun
semanticscholar   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

PERSONALIZED MEDICAL WEB SERVICES IN THE HEALTH CARE SYSTEM OF THE RUSSIAN FEDERATION

open access: yesБюллетень сибирской медицины, 2014
Personal medical records of the patient in electronic form are the basis of modern health care information. With the development of medical technologies for patients have more opportunities to independently monitor various indicators of health. Currently,
D. Ye. Maksimov   +3 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

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