Results 171 to 180 of about 81,170,443 (266)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Trends in patient and public involvement in health research 2000-2024. [PDF]

open access: yesRes Involv Engagem
Cowley S   +7 more
europepmc   +1 more source

Three recommendations for elected representatives & policy makers

open access: yes
We present the 2024 priority recommendations for HRCI and our members. We are asking elected representatives, policy makers and everyone with influence in the health research space to prioritise them, as they plan for the year ahead.
Health Research Charities Ireland
core  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

HRCI Position Paper 2025

open access: yes
In the HRCI Position Paper 2025, we outline the top priorities for both HRCI and our members, aimed at enhancing health research in Ireland. In consultation with our members, Health Research Charities Ireland has developed three asks for elected ...
Health Research Charities Ireland, /
core  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Author Correction: Integrating artificial intelligence tools in health research. [PDF]

open access: yesNPJ Digit Med
Postill G   +9 more
europepmc   +1 more source

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