Results 81 to 90 of about 110,465 (287)

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

open access: yesAdvanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio   +3 more
wiley   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

Nrf2 Expression in CML and AML Patients’ Peripheral Blood Mononuclear Cells Treated by Vitamin D, Carnosic Acid and Curcumin

open access: yesJournal of Pure and Applied Microbiology, 2018
The following study demonstrated the influence of 1,25D/CA and 1,25D/CUR combinations on Nrf2 expression in primary leukemic cells derived from newly diagnosed CML and AML patients of hematological department of Karaganda Regional Clinical Hospital ...
A.G. Zhumina   +9 more
doaj   +1 more source

Germany: Continued 'elite precaution' alongside continued public opposition [PDF]

open access: yes, 2000
Germany is the EU member state with the most difficult marketing situation (besides Austria) as regards genetically modified (gm) crops and food. At the same time, it shows the least administrative effort to respond to the reasons for this situation ...
Dreyer, Marion, Gill, Bernhard
core   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

open access: yesAdvanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang   +9 more
wiley   +1 more source

(Still) A Real and Substantial Mess: The Law of Jurisdiction in Canada [PDF]

open access: yes, 2013
In Morguard Investments Ltd. v. De Savoye, the Supreme Court of Canada established that a court could assert jurisdiction over an out-of-province defendant in cases where there was a real and substantial connection between the forum and the action ...
Monestier, Tanya
core   +3 more sources

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

open access: yesAdvanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu   +20 more
wiley   +1 more source

resorts, hospitals

open access: yesПроект Байкал, 2019
Architecture of resorts and hospitals is a crucial aspect of health in the city. There are a lot of open questions. People bring their diseases to resorts and hospitals. So what emotional charge should architecture of such buildings carry?
Elena Grigoryeva
doaj   +2 more sources

Źródła do dziejów uzdrowisk w zasobie Archiwum Państwowego w Kielcach

open access: yesKwartalnik Historii Kultury Materialnej, 2015
SOURCES TO THE HISTORY OF HEALTH RESORTS IN THE STATE ARCHIVE IN KIELCE The aim of the article is to discuss sources to the history of five health resorts: Busko Zdrój, Solec Zdrój, Ojców, Rabsztyn and Czarniecka Góra.
Hubert Mazur
doaj  

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