Results 81 to 90 of about 110,678 (289)

Tourism development in Ukraine [PDF]

open access: yes, 2015
All prerequisites for development of the tourism industry in Ukraine exist. These include a convenient geographical location, favourable climate, varied terrain, a unique combination of natural and recreational resources, cultural heritage, specialised ...
Demianenko, S., Vartanian, A.
core  

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

open access: yesAdvanced Science, EarlyView.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo   +3 more
wiley   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

Nrf2 Expression in CML and AML Patients’ Peripheral Blood Mononuclear Cells Treated by Vitamin D, Carnosic Acid and Curcumin

open access: yesJournal of Pure and Applied Microbiology, 2018
The following study demonstrated the influence of 1,25D/CA and 1,25D/CUR combinations on Nrf2 expression in primary leukemic cells derived from newly diagnosed CML and AML patients of hematological department of Karaganda Regional Clinical Hospital ...
A.G. Zhumina   +9 more
doaj   +1 more source

His‐MMDM: Multi‐Domain and Multi‐Omics Translation of Histopathological Images with Diffusion Models

open access: yesAdvanced Science, EarlyView.
His‐MMDM is a diffusion model‐based framework for scalable multi‐domain and multi‐omics translation of histopathological images, enabling tasks from virtual staining, cross‐tumor knowledge transfer, and omics‐guided image editing. ABSTRACT Generative AI (GenAI) has advanced computational pathology through various image translation models.
Zhongxiao Li   +13 more
wiley   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

open access: yesAdvanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu   +20 more
wiley   +1 more source

Źródła do dziejów uzdrowisk w zasobie Archiwum Państwowego w Kielcach

open access: yesKwartalnik Historii Kultury Materialnej, 2015
SOURCES TO THE HISTORY OF HEALTH RESORTS IN THE STATE ARCHIVE IN KIELCE The aim of the article is to discuss sources to the history of five health resorts: Busko Zdrój, Solec Zdrój, Ojców, Rabsztyn and Czarniecka Góra.
Hubert Mazur
doaj  

The development of Russian peripheral region. Ecological and geopolitical problems of the region of Caucasian spa resorts [PDF]

open access: yes, 2003
The region of Caucasian spa resorts is now one of the most important tourist regions of Russia. Before the collapse of the USSR 7% of the total number of health facilities of this country was situated in this region.
Piterski, Dmitri, Rattchina, Marina
core  

Higher‐Level Structural Classification of Pseudomonas Cyclic Lipopeptides through Their Bioactive Conformation

open access: yesAdvanced Science, EarlyView.
Solution structures of a series of cyclic lipodepsipeptides from Pseudomonas reveal that these specialized metabolites adopt left‐handed alpha helical conformations of only two types, being either ‘stapled’ or ‘catch‐pole’ helix. The particular modular distribution of the biosynthetic gene clusters is found to determine the extent of their conserved ...
Benjámin Kovács   +9 more
wiley   +1 more source

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