Results 141 to 150 of about 8,841,875 (314)

Hospitals, Health Care Professionals, and Aids: the Right to Know the Health Status of Professionals and Patients [PDF]

, 1989
This article addresses why patients and health care professionals (HCPs) with human immunodeficiency virus (HIV) should have autonomy and privacy rights to choose whether to consent to an HIV test and to disclose their serologic status.
Gostin, Larry
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Current and future temperature suitability for autochthonous transmission of malaria in Canada

International Journal of Health Geographics
Background Malaria continues to be one of the most significant infectious diseases in terms of morbidity and mortality. In many parts of North America, including parts of southern Canada, competent malaria vectors Anopheles quadrimaculatus and Anopheles ...
Kevin Siebels, Victoria Ng, Nicholas Ogden, Steven Schofield, Antoinette Ludwig   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Anthraquinone in Chinese tea: concentration and health risk assessment

Cogent Food & Agriculture
Recently, the safety of anthraquinone (AQ) in Chinese tea has received much attention. This study determined the concentration of AQ in 1573 Chinese tea samples by gas chromatography-tandem mass spectrometry (GC-MS/MS).
Qianqian Xie, Dingguo Jiang, Ling Yong, Xiao Xiao, Dajin Yang, Haixia Sui, Daoyuan Yang, Tong Ou, Yin Wang, Yan Song   +9 more
doaj   +1 more source

Public and Private Health Insurance in Germany: The Ignored Risk Selection Problem [PDF]

While risk selection within the German public health insurance system has received considerable attention, risk selection between public and private health insurers has largely been ignored.
Martina Grunow, Robert Nuscheler
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Risk and Uncertainty in Health Investment [PDF]

Extending the Grossman [12] model of health capital into a stochastic one, we analyze how the presence of Knightian uncertainty about the efficacy of health care affects the optimal health investment behavior of individuals. Using Gilboa and Schmeidler's
Akihisa Shibata, Takao Asano
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Methods for conducting a living evidence profile on mpox: An evidence map of the literature

Cochrane Evidence Synthesis and Methods
Background In May of 2022, several cases of mpox were identified in multiple nonendemic countries and on July 23, 2022 the World Health Organization declared mpox a Public Health Emergency of International Concern.
Kusala Pussegoda, Tricia Corrin, Austyn Baumeister, Dima Ayache, Lisa Waddell   +4 more
doaj   +1 more source