Results 171 to 180 of about 3,230,064 (315)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Unlocking hidden health risks: Exploring community-based screening for kidney disease. [PDF]

Saudi Med J
Albakr RB, Alrowie F, Sandokji IA, Alshammari OA, Mitwalli HA, AlSudais H, Albacker AB, Temsah MH, Mitwalli AH, Alhasan KA.   +9 more
europepmc   +1 more source

Climate change and human health - risks and responses [PDF]

, 2003
Campbell-Lendrum, DH, Corval?n, CF, Ebi, KL, Githeko, A, McMichael, AJ, Scheraga, JD, Woodward, A   +6 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Tick-Borne Viruses in Finland: Public Health Risks, Interventions and Research Insights. [PDF]

Vet Med Sci
Alale TY, Klemola T, Sormunen JJ, Harvala H, Kakkola L, Tikkala J, Vesterinen EJ.   +6 more
europepmc   +1 more source

Mixed Experiences: a study of the childhood narratives of mixed race people related to risks to their mental health and capacity for developing resilience [PDF]

Background: The mixed race child population is growing proportionately faster than any other group. Whilst there is a body of research in this country, albeit small, that looks at the experiences of mixed race children, none of this research examines ...
Morley, Dinah
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Environmental and Human Health Risks of 6PPD and 6PPDQ: Assessment and Implications. [PDF]

Toxics
Zhang S, Tang J, Qiu Z, Huo X, Liu D, Zeng X.   +5 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

The Impact of Incentives on Valuing Health Risks. [PDF]

Health Econ
Gil-Moltó MJ, Hole AR, Andersson H, Godager G.   +3 more
europepmc   +1 more source