Results 91 to 100 of about 7,174,113 (351)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Agradecimento aos revisores

open access: yesABCS Health Sciences, 2020
ABCS Health Sciences
doaj   +1 more source

IPSILATERAL INGUINAL HERNIA IN TODDLERS: IS IT NECESSARY TO EXPLORE OTHER SIDE?

open access: yesJournal of Research in Medical Sciences, 2001
Introduction: Inguinal hernia is one of the most common disease in pediatric surgery. Operation is the only definite treatment for it, yet. Bilateral inguinal exploration is recommended by some authors due to high incidence of bilateral inguinal hernia ...
H.A DAVARI   +1 more
doaj  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Compartment-specific antibody correlates of protection to SARS-CoV-2 Omicron in macaques

open access: yesiScience
Summary: Antibodies represent a primary mediator of protection against respiratory viruses. Serum neutralizing antibodies (NAbs) are often considered a primary correlate of protection.
Xin Tong   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Exploring the impact of AI technostress on physicians’ job insecurity and performance from an empirical multi-hospital study

open access: yesiScience
Summary: This study expands Califf’s technostress model, which explores the psychological stress caused by technology, by integrating “perceived self-esteem threat” as a key stressor driven by the growing influence of medical artificial intelligence (AI),
Chung-Feng Liu, Tzu-Chi Lin, Yen-Ling Ko
doaj   +1 more source

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