Results 171 to 180 of about 7,174,113 (351)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Peer education on HPV: impact on health sciences students' knowledge, awareness, and concern. [PDF]
Kömürcü N, İşbay Aydemi̇r B.
europepmc +1 more source
Factors Affecting Clinical Practice at the Mabel McCombs College of Health Sciences [PDF]
Ms Naomi T. Joe
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Understanding cost variation in medical and health sciences education: An institutional perspective. [PDF]
Osmani AR.
europepmc +1 more source
Perceptions of Undergraduate Students of Allied Health Sciences Program Toward Online Assessments
Poornima Baby +5 more
openalex +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Presentations of Sultan Qaboos University Clinico-Pathologic Conferences
Sultan Qaboos University College of Medicine & Health Sciences and Sultan Qaboos University Hospital, 2014–2015
doaj +1 more source

