Results 41 to 50 of about 6,499,787 (384)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Science diplomacy for plant health
Nature Plants, 2020 Peer ...
Baldissera Giovani +38 more
openaire +7 more sources
The Scoop, Vol. 1 Issue 12, March 2015 [PDF]
, 2015 Latest news and events from the Health Sciences Library in our monthly newsletter for March 2015.https://stars.library.ucf.edu/scoop-vol1/1014/thumbnail ...
Library, Health Sciences
core +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Precision Medicine for the Population-The Hope and Hype of Public Health Genomics [PDF]
arXiv, 2022 Public health is the most recent of the biomedical sciences to be seduced by the trendy moniker "precision." Advocates for "precision public health" (PPH) call for a data-driven, computational approach to public health, leveraging swaths of genomic "big data" to inform public health decision-making. Yet, like precision medicine, PPH oversells the value
arxiv
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Unlocking the Power of Health Datasets and Registries: The Need for Urgent Institutional and National Ownership and Governance Regulations for Research Advancement [PDF]
Journal of Nature and Science of Medicine 2023, Volume 6, Issue 3, 2023 Health datasets have immense potential to drive research advancements and improve healthcare outcomes. However, realizing this potential requires careful consideration of governance and ownership frameworks. This article explores the importance of nurturing governance and ownership models that facilitate responsible and ethical use of health datasets ...
arxiv
Diphthamide synthesis is linked to the eEF2‐client chaperone machinery
FEBS Letters, EarlyView.The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr +4 more
wiley +1 more source
Performance of different support surfaces during experimental resuscitation (CPR)
Heliyon, 2016 The relationship between the efficacy of resuscitation and the mattresses and backboards used in acute care units, has been studied previously. However, few reports focus on the relative efficacy of resuscitation when using mattresses with different ...
Esa Soppi +3 more
doaj +1 more source
The Scoop, Vol. 4 Issue 6, September 2017 [PDF]
, 2017 Latest news and events from the Health Sciences Library in our monthly newsletter for September 2017.https://stars.library.ucf.edu/scoop-vol4/1004/thumbnail ...
Library, Health Sciences
core +1 more source