Results 211 to 220 of about 14,384,820 (305)

GM‐CSF Promotes Neutrophil PD‐L1 Expression Through the VEGFR‐2/STAT6/CSF2 Signaling Axis in Oral Squamous Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
VEGFR‐2 signaling in OSCC activates Src–STAT6‐dependent CSF2 transcription, driving tumor‐derived GM‐CSF secretion. GM‐CSF programs neutrophils to express PD‐L1 through STAT5–mTOR/S6K signaling, suppressing cytotoxic CD8+ T cells. This pathway reveals a tumor–neutrophil immune checkpoint circuit that limits anti‐PD‐1 responsiveness in OSCC.
Fangxing Zhu   +13 more
wiley   +1 more source

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

open access: yesAdvanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu   +7 more
wiley   +1 more source

Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue

open access: yesAdvanced Science, EarlyView.
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg   +19 more
wiley   +1 more source

Multi‐Scale Bionic Structure Constructs Biomass Flame‐Retardant Thermal Insulation Foam Material

open access: yesAdvanced Science, EarlyView.
Inspired by mussel adhesion and hierarchical brick‐and‐mortar architectures, a cellulose‐based biomimetic foam is constructed by anchoring bentonite nanosheets onto a polydopamine‐decorated cellulose nanofiber network. The resulting foam combines low thermal conductivity with intrinsic flame retardancy and full biodegradability, presenting a ...
Jianming Liao   +10 more
wiley   +1 more source

Contribution and influence of social capital on corruption in the health sector: a view through the lens of service users. [PDF]

open access: yesBMJ Glob Health
Obi CE   +7 more
europepmc   +1 more source

Decoupling Electronic–Ionic Transport and Catalysis Enables High‐Performance, Chemically Stable Sr‐Free Air Electrodes for High‐Temperature Solid Oxide Cells

open access: yesAdvanced Science, EarlyView.
A Sr‐free air electrode for high‐temperature solid oxide cells is designed by independently tailoring electronic conduction, ionic transport, and surface catalysis using complementary Sr‐free phases and infiltrated nanocatalysts. It delivers performance comparable to state‐of‐the‐art Sr‐containing electrodes while completely suppressing Cr‐induced ...
Ji‐eun Won   +10 more
wiley   +1 more source

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