Results 41 to 50 of about 16,821,222 (259)

The mental health care model in Brazil: analyses of the funding, governance processes, and mechanisms of assessment

open access: yesRevista de Saúde Pública
OBJECTIVE This study aims to analyze the current status of the mental health care model of the Brazilian Unified Health System, according to its funding, governance processes, and mechanisms of assessment.
Thiago Lavras Trapé   +1 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

International Hospital Performance Assessment: Developing a Questionnaire

open access: yesNovelty in Biomedicine, 2018
Background: As there is no valid questionnaire for assessing international hospital performance from providers’ perspective, this study aimed to develop a reliable as well as valid questionnaire for Iranian hospitals.Materials and Methods: To develop the
Mona Mohammadnia   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

International Hospitals’ Performance Variables: A Comparative Study

open access: yesNovelty in Biomedicine, 2019
Background: To define a series of variable that separates international hospitals from other ones is the main aim of this study. Materials and Methods: After choosing some countries in the worldwide, two hospitals, which were the leaders on international
Mona Mohammadnia   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Is incentive spirometry beneficial for patients with lung cancer receiving video-assisted thoracic surgery?

open access: yesBMC Pulmonary Medicine, 2019
Background The effectiveness of Incentive spirometry (IS) in patients undergoing video-assisted thoracic surgery (VATS) remains lacking. We conducted a population-based study to investigate the effectiveness of IS on patients with lung cancers following ...
Chin-Jung Liu   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Collegiate management in inpatient pediatric unit from health professionals’ perspective

open access: yesO Mundo da Saúde, 2019
The hospitals make up the tertiary level of Health Care Network, which include sets of procedures in the context of the Health System, it involves high technology and high cost and integrates other health care levels.
Maria José Menezes Brito   +4 more
doaj  

Implementation of tobacco control measures in the Gulf Cooperation Council countries, 2008–2020

open access: yesSubstance Abuse Treatment, Prevention, and Policy, 2021
Background The World Health Organization (WHO) Framework Convention on Tobacco Control (FCTC) was developed to assist nations in reducing the demand and supply of tobacco.
Sarah S. Monshi, Jennifer Ibrahim
doaj   +1 more source

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