Results 201 to 210 of about 3,605,266 (385)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

30 years of youth system of care lessons learned - a qualitative study of Hawai'i's partnership with the Substance Abuse and Mental Health Services Administration. [PDF]

BMC Health Serv Res
Okamura KH, Jackson D, Ching DLC, Suh DE, Hartsock TLR, Hee PJ, Shimabukuro SK.   +6 more
europepmc   +1 more source

The Substance Abuse and Mental Health Services Administration Buprenorphine Practitioner Locator Misrepresents Access to Buprenorphine

, 2021
Precious Anyanwu, Tyler J. Varisco, Matthew A. Wanat, Shweta Bapat, Kasey Claborn, J. Douglas Thornton   +5 more
openalex   +2 more sources

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Media Trends for the Substance Abuse and Mental Health Services Administration 800-662-HELP Addiction Treatment Referral Services After a Celebrity Overdose.

JAMA Intern Med, 2019
Ayers JW, Nobles AL, Dredze M.
europepmc   +1 more source

Rapid Growth of Mental Health Services at Community Health Centers

Administration and Policy in Mental Health and Mental Health Services Research, 2019
T. Bruckner, Parvati Singh, L. Snowden, Jangho Yoon, B. Chakravarthy   +4 more
semanticscholar   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Examining the Potential Role of Opioid Settlement Funds in the Face of Impending Federal Budget Reductions for Substance Use Disorders. [PDF]

Health Serv Res
Lindenfeld Z, Mauri AI, Bandara S, Cantor JH, McBain RK, Winiker A.   +5 more
europepmc   +1 more source