Results 51 to 60 of about 16,821,222 (259)

Service provision and barriers to care for homeless people with mental health problems across 14 European capital cities [PDF]

, 2012
Background Mental health problems are disproportionately higher amongst homeless people. Many barriers exist for homeless people with mental health problems in accessing treatment yet little research has been done on service provision and quality of care
Greacen, Tim, Straßmayr, Christa, Jacek Moskalewicz, Soares, Joaquim, Kluge Ulrike, Barry Margaret M, Priebe, Stefan, Schene, AH, Holcnerova, Petra, Gaddini, Andrea, Soares Joaquim J F, Diaz-Olalla, Jose Manuel, Petra Holcnerová, Soares, JJF, Gaddini Andrea, Barry, Margaret M, Aleksandra Matanov, Margaret M Barry, Barry, Margaret M., Barros, H, Greacen, T, Greacen Tim, Canavan, Reamonn, Díaz-Olalla José, Barros, Henrique, Kluge, U, Schene, Aart, Moskalewicz, Jacek, Aart H Schene, Manuel Diaz-Olalla, J, Priebe, S, Matanov, Aleksandra, Nicaise Pablo, Canavan Réamonn, Nicaise, Pablo, Soares, Joaquim J. F.,, Henrique Barros, Canavan, R, Ulrike Kluge, Strassmayr, C, Nicaise, P, Réamonn Canavan, Barros Henrique, Barry, MM, Tim Greacen, Soares, Joaquim J. F., Joaquim J F Soares, Priebe Stefan, Barry, Margaret, Gabor Edina, Stefan Priebe, Matanov Aleksandra, Gabor, E, José Manuel Díaz-Olalla, Holcnerova, P, Holcnerová Petra, Matanov, A, Schene Aart H, Moskalewicz Jacek, Christa Straßmayr, Andrea Gaddini, Schene, Aart H, Pablo Nicaise, Gabor, Edina, Kluge, Ulrike, Edina Gabor, Soares, Joaquim J F, Moskalewicz, J, Straßmayr Christa, Gaddini, A, Díaz-Olalla, José M   +70 more
core   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Community health status report. [Ohio]

, 2000
Title from caption of PDF files (viewed on Aug. 14, 2007).; "July 2000."; Harvested from the web on 8/15/07Statistical reports of health indicators for each county in Ohio.Statistical reports of health indicators for Allen County ...
U.S. Dept. of Health and Human Services, Health Resources and Services Administration.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Team- and Problem-Based Learning in Health Services: A Systematic Literature Review of Recent Initiatives in the United States

Education Sciences
The COVID-19 pandemic caused a sudden shift to virtual platforms. Physical distance and limited experience with both synchronous and asynchronous teamwork at work and school hampered problem-solving and the development of critical thinking skills.
Eileen S. Alexander, Ashley A. White, Ashley Varol, Kacey Appel, Cristian Lieneck   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Mental health transformation state incentive grant; Connecticut revised 2008 CMHP (draft)

, 2008
Rev.; Title from PDF cover (viewed June 18, 2009).; At head of title: State of Connecticut.; "February 2008."; Updates: A comprehensive mental health plan for the state of Connecticut : mental health transformation state incentive grant ; submitted to ...

core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source