Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Working for God? evualuating service delivery of religious not-for-profit health care providers in Uganda [PDF]
Reinikka and Svensson exploit a unique micro-level data set on primary health care facilities in Uganda to address the question: What motivates religious not-for-profit (RNP) health care providers?
Reinikka, Ritva, Svensson, Jakob
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The effect of minimum volume standards in hospitals (MIVOS): a systematic review
BMJ OpenObjectives The relationship between the volume of medical procedures conducted in hospitals and the resulting health outcomes has been described for various surgical and non-surgical medical interventions.
Dawid Pieper +7 more
doaj +1 more source
'I wouldn't trust it …' Digital transformation of young people's sexual health services: a systems-informed qualitative enquiry. [PDF]
BMJ Public Health, 2023 Bennett C +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Supporting safe motherhood : a review of financial trends : summary [PDF]
An estimated 500,000 women, 99 percent of them from the developing world, die each year from pregnancy-related causes. About three quarters of these deaths are the direct result of obstetrical complications -- hemorrhage, infection, toxemia, obstructed ...
Howard, L. M.
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Assessing preventable hospitalisation indicators (APHID): protocol for a data-linkage study using cohort study and administrative data [PDF]
, 2012 Introduction Potentially preventable hospitalisation (PPH) has been adopted widely by international health systems as an indicator of the accessibility and overall effectiveness of primary care. The Assessing Preventable Hospitalisation InDicators (APHID)
Blyth, F.M. +5 more
core +2 more sources
A situational analysis of child and adolescent mental health services and systems in the Western Cape Province of South Africa. [PDF]
Child Adolesc Psychiatry Ment Health, 2022 Mokitimi S, Schneider M, de Vries PJ.
europepmc +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
The effects of a fee-waiver program on health care utilization among the poor : evidence from Armenia [PDF]
This study examines the impact of a fee-waiver program for basic medical services on health care utilization in Armenia. Because of the reduction in public financing of health services and decentralization and increased privatization of health care ...
Chaudhury, Nazmul +2 more
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