Results 111 to 120 of about 1,655,559 (396)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Evaluation of Uptake of COVID-19 Temporary Allied Health Services for Residential Aged Care in Australia. [PDF]

J Am Med Dir Assoc, 2023
Caughey GE, Collier L, Cations M, Wesselingh S, Inacio MC.   +4 more
europepmc   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Home care in the Federal District: factors associated with the first occurrence of acute lower respiratory infection and death

Revista da Sociedade Brasileira de Medicina Tropical
INTRODUCTION: We aimed to evaluate the frequency and associated factors of acute respiratory infection and death among home care patients in Sobradinho/DF, Brazil. METHODS: Data were obtained from patients’ medical records.
Leny Nunes de Barros, Maria Regina Fernandes de Oliveira   +1 more
doaj   +1 more source

The relationship between quality of life, health and care transition: an empirical comparison in an older post-acute population

Health and Quality of Life Outcomes, 2012
Background The aim of this study was to explore, via empirical comparison, the relationship between quality of life, as measured by the ICECAP-O capability index (a new instrument designed to measure and value quality of life in older people), with both ...
Couzner Leah, Ratcliffe Julie, Crotty Maria   +2 more
doaj   +1 more source

Health Status and Preventive Health Services Among Reproductive-Aged Women in Treatment for Opioid Use Disorder. [PDF]

Womens Health Rep (New Rochelle), 2022
Short VL, Hand DJ, Pyfer L, Steiger H, Gannon M, Jaffe G, Abatemarco DJ.   +6 more
europepmc   +1 more source

Health-saving behavior and quality of life of military pensioners of working age in the process of their re-socialization after discharge from military service: qualitative and quantitative study [PDF]

, 2023
Nadezhda V. Prisyazhnaya, Evgeniy V. Dubogray, Ekaterina G. Аgapova   +2 more
openalex   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Organization and support as an essential part of group exercise programs for older people with dementia: an end-user interview study

Frontiers in Sports and Active Living
IntroductionDevelopment of accessible group exercise sessions is warranted for home-dwelling older people with cognitive impairment or dementia. This study aims to explore the experiences of participants in a group exercise session organized with ...
Kristin Taraldsen, Arnhild J. Nygård, Elisabeth Boulton, Guro Grønningsæter, Marit H. Erland, Nina Waldenstrøm, Linda Johnsen, Gro G. Tangen, Gro G. Tangen, Randi Granbo   +9 more
doaj   +1 more source

Preferences for accessing sexual health services among middle-aged and older adults in the UK: a study protocol for a discrete choice experiment using mixed methods. [PDF]

BMJ Open, 2023
Kpokiri E, Pan SW, Ong JJ, Greaves E, Khan J, Bowen S, Jannaway T, Terris-Prestholt F, Tanton C, Kuper H, Shakespeare T, Tucker JD, Wu D.   +12 more
europepmc   +1 more source