Results 171 to 180 of about 1,372,242 (337)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
A Labor Market Approach to the Crisis of Health Care Professionals in Africa [PDF]
This paper adopts a labor market economics perspective to understanding the crisis of healthcare professionals in Africa. Five challenges resulting from this crisis are identified: a production challenge, an underutilization challenge, a distributional ...
Andalón, Mabel, Fields, Gary S
core +1 more source
E. Lattie +5 more
semanticscholar +1 more source
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Theoretical insights into the development of health insurance in low-income countries [PDF]
This Discussion Paper is concerned with the development of risk-sharing systems for health, in low- and middle-income countries. It questions whether insurance theory developed in wealthier economies, in particular the central ideas of adverse selection ...
Matthew Jowett
core
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Fez-se um estudo descritivo, retrospectivo do Perfil Sócio-Econômico da População que demanda Assistência Médico-Hospitalar em uma Região do Nordeste do Estado de São Paulo (Brasil), comparando-se os resultados de pesquisas anteriores.
Rafael de Jesus Montero D'Oleo +1 more
doaj
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini +7 more
wiley +1 more source
The profile of frequent user of a Multipurpose Emergency Service
Objective: to analyze the profile of frequent users of a Multipurpose Emergency Service in the Azores, Portugal, relating sociodemographic, clinical and time characteristics.
Alexandra Torres de Medeiros +2 more
doaj

