KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini+24 more
wiley +1 more source
Digital preventive measures for arterial hypertension (DiPaH) - a mixed-methods study protocol for health services research. [PDF]
Bruch D+12 more
europepmc +1 more source
ABSTRACT Dopaminergic medication and deep brain stimulation (DBS) improve motor symptoms in Parkinson's disease (PD), but levodopa response alone may not predict DBS outcomes. We retrospectively analyzed 19 PD patients undergoing levodopa challenges with and without prior transcranial direct current stimulation targeting a defined PD response network ...
Lukas L. Goede+3 more
wiley +1 more source
Smad2 and 3 Mediate Transforming Growth Factor-β1-Induced Inhibition of Chondrocyte Maturation**The work was supported by National Health Services Grant AR-38945 (to R.J.O.) and an Orthopaedic Research Education Foundation Award (to C.M.F.). [PDF]
Cristin M. Ferguson+5 more
openalex +1 more source
[Health services research in acute pain medicine : Where do we come from in Germany?] [PDF]
Nestler N, Maier C, Osterbrink J.
europepmc +1 more source
ABSTRACT Objective People with HIV (PWH) on antiretroviral therapy (ART) still experience neurocognitive dysfunction and accelerated brain volume loss. To assess whether the serotonergic and dopaminergic systems are affected, we used [11C]DASB positron emission tomography (PET) to assess presynaptic serotonergic function and [18F]FDOPA PET to measure ...
Chuen‐Yen Lau+12 more
wiley +1 more source
Priority setting in public health and health services research [PDF]
Norman Carson, Zahid Ansari, W. G. Hart
openalex +1 more source
A Comparison of Variance Estimators for Logistic Regression Models Estimated Using Generalized Estimating Equations (GEE) in the Context of Observational Health Services Research. [PDF]
Austin PC.
europepmc +1 more source
Correction to "Transactional and transformative diversity, equity, and inclusion activities in health services research departments". [PDF]
europepmc +1 more source