Results 281 to 290 of about 12,072,876 (365)

Investigation and analysis of sleep and mental health status among MEFCs. [PDF]

Front Psychiatry
Yu K, Song S, Wu L, Chen Z.
europepmc   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

A 5-Year Follow-Up Case Report Documenting Stable Peri-Implant Health Status Around a Re-Osseointegrated Implant. [PDF]

Clin Case Rep
Lind KH, Berg E, Ulvik IM, Leknes KN.
europepmc   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Effect of age and disease on saliva and serum biomarkers of stress, inflammation, immunity, redox and general health status in pigs. [PDF]

Sci Rep
Tecles F, Martínez-Martínez A, Crespo-Piazuelo D, López-Martínez MJ, Yeste-Vizcaíno N, Goyena E, Cerón JJ, Martinez-Subiela S, González-Bulnes A, Muñoz-Prieto A.   +9 more
europepmc   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Joint health status in people with moderate hemophilia A: a cross-sectional multicenter study. [PDF]

Res Pract Thromb Haemost
Calcaterra IL, Picasso F, Valeri F, Baldacci E, Napolitano M, Guerrino C, Zanon E, Santoro C, Siragusa S, Martinoli C, Di Minno MND.   +10 more
europepmc   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Life's Essential 8 cardiovascular health status of 18-69-year-old individuals in France. [PDF]

Am J Prev Cardiol
Deraz O, Kab S, Touvier M, Jouven X, Goldberg M, Zins M, Empana JP.   +6 more
europepmc   +1 more source

Sex differences in health status trajectories among Chinese angina patients: a post-hoc analysis of the GREAT multicenter prospective cohort. [PDF]

BMC Cardiovasc Disord
Wu Y, Zhao X, Cheng G, Sun L, Liu Y, Xu S, Wu L, Wei Y, Liu W, Miao L, Zhang Q, Ma C, Zeng Y, Du X.   +13 more
europepmc   +1 more source